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Apicomplexa micropore: history, function, and formation (2024)
Journal Article
Yang, J., Long, S., Hide, G., Lun, Z.-R., & Lai, D.-H. (2024). Apicomplexa micropore: history, function, and formation. Trends in Parasitology, 40(5), S1471-4922(24)00079-5. https://doi.org/10.1016/j.pt.2024.03.008

The micropore, a mysterious structure found in apicomplexan species, was recently shown to be essential for nutrient acquisition in Plasmodium falciparum and Toxoplasma gondii. However, the differences between the micropores of these two parasites qu... Read More about Apicomplexa micropore: history, function, and formation.

Synthesis and Characterisation of Metal Organic Frameworks for Use as Drug Delivery Systems in Neuroblastoma Therapy (2024)
Thesis
Nduka, I. O. (2024). Synthesis and Characterisation of Metal Organic Frameworks for Use as Drug Delivery Systems in Neuroblastoma Therapy. (Thesis). University of Salford

Gliotoxin, a secondary metabolite isolated from the fungi, Aspergillus fumigatus has
shown cytotoxic activity against neuroblastoma, a type of cancer accounting for 15%
of all childhood cancer-related deaths. But as with all other chemotherapeutic... Read More about Synthesis and Characterisation of Metal Organic Frameworks for Use as Drug Delivery Systems in Neuroblastoma Therapy.

The Toxoplasma monocarboxylate transporters are involved in the metabolism within the apicoplast and are linked to parasite survival (2024)
Journal Article
Dong, H., He, K., Yang, J., Zheng, W., Lai, D., Liu, J., …Long, S. (2024). The Toxoplasma monocarboxylate transporters are involved in the metabolism within the apicoplast and are linked to parasite survival. eLife, 12, RP88866. https://doi.org/10.7554/elife.88866.3

The apicoplast is a four-membrane plastid found in the apicomplexans, which harbors biosynthesis and organelle housekeeping activities in the matrix. However, the mechanism driving the flux of metabolites, in and out, remains unknown. Here, we used T... Read More about The Toxoplasma monocarboxylate transporters are involved in the metabolism within the apicoplast and are linked to parasite survival.

Calcium signaling in endothelial and vascular smooth muscle cells: sex differences and the influence of estrogens and androgens (2024)
Journal Article
Asunción-Alvarez, D., Palacios, J., Ybañez-Julca, R. O., Rodriguez-Silva, C. N., Nwokocha, C., Cifuentes, F., & Greensmith, D. J. (2024). Calcium signaling in endothelial and vascular smooth muscle cells: sex differences and the influence of estrogens and androgens. American journal of physiology. Heart and circulatory physiology, 326(4), H950-H970. https://doi.org/10.1152/ajpheart.00600.2023

Calcium signaling in vascular endothelial cells (ECs) and smooth muscle cells (VSMCs) is essential for the regulation of vascular tone. However, the changes to intracellular Ca2+ concentrations are often influenced by sex differences. Furthermore, a... Read More about Calcium signaling in endothelial and vascular smooth muscle cells: sex differences and the influence of estrogens and androgens.

Self-assembling ferritin nanoplatform for the development of infectious hematopoietic necrosis virus vaccine (2024)
Journal Article
Ahmadivand, S., Krpetic, Z., Martínez, M. M., Ordoñez, M. G., Roher, N., & Palić, D. (2024). Self-assembling ferritin nanoplatform for the development of infectious hematopoietic necrosis virus vaccine. Frontiers in Immunology, 15, 1346512. https://doi.org/10.3389/fimmu.2024.1346512

Self-assembling protein nanoparticles are used as a novel vaccine design platform to improve the stability and immunogenicity of safe subunit vaccines, while providing broader protection against viral infections. Infectious Hematopoietic Necrosis vir... Read More about Self-assembling ferritin nanoplatform for the development of infectious hematopoietic necrosis virus vaccine.

The transplant rejection response involves neutrophil and macrophage adhesion-mediated trogocytosis and is regulated by NFATc3 (2024)
Journal Article
Zhao, S., Hu, Y., Yang, B., Zhang, L., Xu, M., Jiang, K., …Shen, J. (in press). The transplant rejection response involves neutrophil and macrophage adhesion-mediated trogocytosis and is regulated by NFATc3. Cell Death and Disease, 15(1), 75. https://doi.org/10.1038/s41419-024-06457-4

The anti-foreign tissue (transplant rejection) response, mediated by the immune system, has been the biggest obstacle to successful organ transplantation. There are still many enigmas regarding this process and some aspects of the underlying mechanis... Read More about The transplant rejection response involves neutrophil and macrophage adhesion-mediated trogocytosis and is regulated by NFATc3.

Prevalence of Eimeria Species, Detected by ITS1-PCR Immobilized on FTA Cards, in Future Laying Hens and Breeding Hens in Six Provinces in Northeastern Algeria (2024)
Journal Article
Ayadi, O., Djemai, S., & Hide, G. (2024). Prevalence of Eimeria Species, Detected by ITS1-PCR Immobilized on FTA Cards, in Future Laying Hens and Breeding Hens in Six Provinces in Northeastern Algeria. Acta parasitologica / Witold Stefański Institute of Parasitology, https://doi.org/10.1007/s11686-023-00773-z

Purpose
Avian coccidiosis is an important and widely distributed disease that affects global agricultural economies through losses. In Algeria, there is limited epidemiological and ecological knowledge about this disease and this hinders implementat... Read More about Prevalence of Eimeria Species, Detected by ITS1-PCR Immobilized on FTA Cards, in Future Laying Hens and Breeding Hens in Six Provinces in Northeastern Algeria.