All Outputs (3)

NAPO as a novel marker for apoptosis (2001)
Journal Article
Sayan, B., Ince, G., Sayan, A., & Ozturk, M. (2001). NAPO as a novel marker for apoptosis. Journal of Cell Biology, 155(5), 719-724. https://doi.org/10.1083/jcb.200106044

Apoptosis or programmed cell death plays a pivotal role in embryonic development and maintenance of homeostasis. It is also involved in the etiology of pathophysiological conditions such as cancer, neurodegenerative, autoimmune, infectious, and heart... Read More about NAPO as a novel marker for apoptosis.

Acquired expression of transcriptionally active p73 in hepatocellular carcinoma cells (2001)
Journal Article
Sayan, A., Sayan, B., Findikli, N., & Ozturk, M. (2001). Acquired expression of transcriptionally active p73 in hepatocellular carcinoma cells. Oncogene, 20, 5111-5117. https://doi.org/10.1038/sj.onc.1204669

p53 and p73 proteins activate similar target genes and induce apoptosis and cell cycle arrest. However, p53, but not p73 is considered a tumour-suppressor gene. Unlike p53, p73 deficiency in mice does not lead to a cancer-prone phenotype, and p73 gen... Read More about Acquired expression of transcriptionally active p73 in hepatocellular carcinoma cells.

A monoclonal antibody against DNA binding helix of p53 protein (2001)
Journal Article
Yolcu, E., Sayan, B., Yagci, T., Cetin-Atalay, R., Soussi, T., Yurdusev, N., & Ozturk, M. (2001). A monoclonal antibody against DNA binding helix of p53 protein. Oncogene, 20, 1398-1401. https://doi.org/10.1038/sj.onc.1204240

Three monoclonal antibodies (Mabs) were generated against p53 DNA-binding core domain. When tested by immunoprecipitation, Western blot and immunofluorescence techniques, Mab 9E4, as well as 7D3 and 6B10 reacted with both wild-type and various mutant... Read More about A monoclonal antibody against DNA binding helix of p53 protein.