Skip to main content

Research Repository

Advanced Search

All Outputs (4)

The Theranostic Role of Small Extracellular Vesicle Mediated microRNA in Medulloblastoma (2024)
Thesis
Amusan, O. (2024). The Theranostic Role of Small Extracellular Vesicle Mediated microRNA in Medulloblastoma. (Thesis). University of Salford

Small extracellular vesicles (sEVs) cargo can potentially alter response to chemotherapy, indicating specific cargo as a potential theranostic biomarker. In this study, we explored miRNAs mediated sEVs for chemotherapy associated biomarkers. We took... Read More about The Theranostic Role of Small Extracellular Vesicle Mediated microRNA in Medulloblastoma.

Exploring potential inhibitors of the HGF-Met signalling pathway as a prospective treatment for paediatric medulloblastoma (2021)
Thesis
Hoyles, N. Exploring potential inhibitors of the HGF-Met signalling pathway as a prospective treatment for paediatric medulloblastoma. (Dissertation). University of Salford

Understanding the function of the HGF-Met signalling axis could present opportunities for new therapeutic treatments for cancer patients. The brain tumour Medulloblastoma is the leading cause of cancer-related death in children and infants meaning re... Read More about Exploring potential inhibitors of the HGF-Met signalling pathway as a prospective treatment for paediatric medulloblastoma.

Mechanisms of medulloblastoma vulnerability and new targeted therapies (2020)
Thesis
Buzzetti, M. Mechanisms of medulloblastoma vulnerability and new targeted therapies. (Thesis). University of Salford

Medulloblastoma (MB) is the most common malignant paediatric brain tumour accounting for about 20% of all childhood brain cancers. Over the last decade, a consensus has been reached over the existence of 4 main molecular subtypes, known as WNT-activa... Read More about Mechanisms of medulloblastoma vulnerability and new targeted therapies.