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MYC is a major determinant of mitotic cell fate (2015)
Journal Article
Topham, C., Tighe, A., Ly, P., Bennett, A., Sloss, O., Nelson, L., …Taylor, S. (2015). MYC is a major determinant of mitotic cell fate. Cancer Cell, 28(1), 129-140. https://doi.org/10.1016/j.ccell.2015.06.001

Taxol and other antimitotic agents are frontline chemotherapy agents but the mechanisms responsible for patient benefit remain unclear. Following a genome-wide siRNA screen, we identified the oncogenic transcription factor Myc as a taxol sensitizer.... Read More about MYC is a major determinant of mitotic cell fate.