All Outputs (5)

The detection and characterisation of novel alkyl spin-adducts of PBN and its derivatives using capillary gas chromatography coupled to electron-ionisation mass spectrometry (2021)
Thesis
Zafar, M. (2021). The detection and characterisation of novel alkyl spin-adducts of PBN and its derivatives using capillary gas chromatography coupled to electron-ionisation mass spectrometry. (Thesis). University of Salford

Free radical induced oxidative stress has been reported to be involved in several diseases such as diabetes mellitus, neurodegenerative disorders, cardiovascular diseases (atherosclerosis and hypertension), respiratory diseases (asthma), cataract dev... Read More about The detection and characterisation of novel alkyl spin-adducts of PBN and its derivatives using capillary gas chromatography coupled to electron-ionisation mass spectrometry.

Detection and analysis of spin trapped radical adducts using thermal desorption gas chromatography mass spectrometry (TD-GC-MS) (2018)
Thesis
Manzoor, K. (2018). Detection and analysis of spin trapped radical adducts using thermal desorption gas chromatography mass spectrometry (TD-GC-MS). (Thesis). University of Salford

Certain oxygen free radicals are produced constantly in cells by metabolism and
exogenous agents. Some, such as the hydroxyl radical, may react with various
biomolecules like DNA, lipids or proteins, and thus be involved in the pathogenesis of
var... Read More about Detection and analysis of spin trapped radical adducts using thermal desorption gas chromatography mass spectrometry (TD-GC-MS).

Cellular biochemical and experimental therapeutic studies of L-glutamine and L-asparagine depletion for paediatric sarcoma cells (2011)
Thesis
Allsup, J. Cellular biochemical and experimental therapeutic studies of L-glutamine and L-asparagine depletion for paediatric sarcoma cells. (Thesis). University of Salford

The aim of this project was to investigate the cellular biochemical and experimental therapeutic effects of L-glutamine (gin) and L-asparagine (asn) depletion for
paediatric sarcoma cells. The work presented in this thesis describes preclinical stud... Read More about Cellular biochemical and experimental therapeutic studies of L-glutamine and L-asparagine depletion for paediatric sarcoma cells.

A study of the cytotoxic effects of methionine depletion in human brain tumour cell lines (2007)
Thesis
Najim, N. A study of the cytotoxic effects of methionine depletion in human brain tumour cell lines. (Thesis). Salford : University of Salford

The aim of this project was to investigate the importance of methionine depletion as a cause
of cytotoxicity for paediatric CNS tumour cell lines, and also to investigate the in vitro
cellular biochemical responses, as measured by changes in cellul... Read More about A study of the cytotoxic effects of methionine depletion in human brain tumour cell lines.

In vitro analysis of volatile organic compounds in search of potential biomarkers of lung cancer
Thesis
Schmidt, K. (in press). In vitro analysis of volatile organic compounds in search of potential biomarkers of lung cancer. (Thesis). University of Salford

Lung cancer is a leading cause of death from cancer worldwide. An early diagnosis and
appropriate treatment are crucial in reducing mortality among people suffering from the
disease. Therefore, one of the main focuses of lung cancer studies is on a... Read More about In vitro analysis of volatile organic compounds in search of potential biomarkers of lung cancer.