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Electrochemical detection of asparaginase antibodies using bifunctionalized carbon interfaces (2023)
Journal Article
Marshall, D., & Lehr, J. (in press). Electrochemical detection of asparaginase antibodies using bifunctionalized carbon interfaces. Electroanalysis, https://doi.org/10.1002/elan.202200456

The early detection of anti-asparaginase biomarker can facilitate timely modification of asparaginase chemotherapy, thereby avoiding serious complications. Herein we describe the preparation of a novel electrochemical biosensing interface for rapid d... Read More about Electrochemical detection of asparaginase antibodies using bifunctionalized carbon interfaces.

Label‐free Selective Detection of Protein Markers in the Picomolar Range via a Convenient Voltammetric Sensing Strategy (2021)
Journal Article
Chen, C., Chen, C., & Lehr, J. (2021). Label‐free Selective Detection of Protein Markers in the Picomolar Range via a Convenient Voltammetric Sensing Strategy. Electroanalysis, 33(3), 563-567. https://doi.org/10.1002/elan.202060308

AbstractA convenient strategy for the preparation of label‐free selective protein biomarker sensors is presented. After formation of a ferrocene terminated monolayer on a gold electrode using thiol chemistry, grafting of an antifouling phenylalanine... Read More about Label‐free Selective Detection of Protein Markers in the Picomolar Range via a Convenient Voltammetric Sensing Strategy.

Mapping the ionic fingerprints of molecular monolayers (2017)
Journal Article
Lehr, J., Weeks, J., Santos, A., Feliciano, G., Nicholson, M., Davis, J., & Bueno, P. (2017). Mapping the ionic fingerprints of molecular monolayers. Physical Chemistry Chemical Physics, 19(23), 15098-15109. https://doi.org/10.1039/c7cp01500c

We have previously proposed, and experimentally resolved, an ionic charge relaxation model for redox inactive self-assembled monolayers (SAMs) on metallic electrodes in contact with a liquid electrolyte. Here we analyse, by capacitance spectroscopy,... Read More about Mapping the ionic fingerprints of molecular monolayers.

Ratiometric oxygen sensing using lanthanide luminescent emitting interfaces (2015)
Journal Article
Lehr, J., Tropiano, M., Beer, P., Faulkner, S., & Davis, J. (2015). Ratiometric oxygen sensing using lanthanide luminescent emitting interfaces. Chemical Communications, 51(88), 15944-15947. https://doi.org/10.1039/c5cc05738h

Herein we describe the first example of a ratiometric lanthanide luminescent oxygen sensing interface. Immobilisation of terbium and europium cyclen complexes on glass substrates was achieved by a novel aryl nitrene photografting approach. The result... Read More about Ratiometric oxygen sensing using lanthanide luminescent emitting interfaces.

Reversible redox modulation of a lanthanide emissive molecular film (2015)
Journal Article
Lehr, J., Tropiano, M., Beer, P., Faulkner, S., & Davis, J. (2015). Reversible redox modulation of a lanthanide emissive molecular film. Chemical Communications, 51(30), 6515-6517. https://doi.org/10.1039/c5cc01097g

Herein we demonstrate redox switchable emission from a sensitised, europium–ferrocene containing, molecular film assembled by a novel nitrene-based strategy. Electrochemical modulation of europium emission upon switching the ferrocene moiety's redox... Read More about Reversible redox modulation of a lanthanide emissive molecular film.

Graphene oxide interfaces in serum based autoantibody quantification (2014)
Journal Article
Xu, Q., Cheng, H., Lehr, J., Patil, A., & Davis, J. (2015). Graphene oxide interfaces in serum based autoantibody quantification. Analytical Chemistry, 87(1), 346-350. https://doi.org/10.1021/ac503890e

A reliable quantification of protein markers will undoubtedly underpin profound developments in disease surveillance, diagnostics, and improved therapy. Although there potentially exist numerous means of achieving this, electrochemical impedimetric t... Read More about Graphene oxide interfaces in serum based autoantibody quantification.

Formation of thick aminophenyl films from aminobenzenediazonium ion in the absence of a reduction source (2014)
Journal Article
Simons, B., Lehr, J., Garrett, D., & Downard, A. (2014). Formation of thick aminophenyl films from aminobenzenediazonium ion in the absence of a reduction source. Langmuir, 30(17), 4989-4996. https://doi.org/10.1021/la501217n

Aminophenyl films, electrografted to conducting substrates from a solution of the corresponding diazonium ion, are a useful platform for building up functional surfaces. In our hands, reproducible preparation of aminophenyl films via electrografting... Read More about Formation of thick aminophenyl films from aminobenzenediazonium ion in the absence of a reduction source.

Exploiting lanthanide luminescence in supramolecular assemblies (2014)
Journal Article
Lehr, J., Beer, P., Faulkner, S., & Davis, J. (2014). Exploiting lanthanide luminescence in supramolecular assemblies. Chemical Communications, 50(43), 5678-5687. https://doi.org/10.1039/c4cc01138d

Lanthanide ions, due to their unique photo-physical characteristics, have attracted considerable attention in recent years. Their long lifetimes, sharp, well-defined emission bands, and designable environmental sensitivity make them ideal for integra... Read More about Exploiting lanthanide luminescence in supramolecular assemblies.

Label-free capacitive diagnostics : exploiting local redox probe state occupancy (2014)
Journal Article
Lehr, J., Fernandes, F., Bueno, P., & Davis, J. (2014). Label-free capacitive diagnostics : exploiting local redox probe state occupancy. Analytical Chemistry, 86(5), 2559-2564. https://doi.org/10.1021/ac403727h

An electrode surface confined redox group contributes to a substantial potential-dependent interfacial charging that can be sensitively probed and frequency-resolved by impedance-derived capacitance spectroscopy. In utilizing the sensitivity of this... Read More about Label-free capacitive diagnostics : exploiting local redox probe state occupancy.

Anion sensing by solution- and surface-assembled osmium(II) bipyridyl rotaxanes (2013)
Journal Article
Lehr, J., Lang, T., Blackburn, O., Barendt, T., Faulkner, S., Davis, J., & Beer, P. (2013). Anion sensing by solution- and surface-assembled osmium(II) bipyridyl rotaxanes. Chemistry - A European Journal, 19(47), 15898-15906. https://doi.org/10.1002/chem.201302886

We report the preparation of [2]rotaxanes containing an electrochemically and optically active osmium(II) bipyridyl macrocyclic component mechanically bonded with cationic pyridinium axles. Such interlocked host systems are demonstrated to recognise... Read More about Anion sensing by solution- and surface-assembled osmium(II) bipyridyl rotaxanes.

Preparation and electrochemical performance of Li<inf>x</inf>MnO <inf>2</inf> materials by a reduction and lithiation method (2013)
Journal Article
Lehr, J., Dose, W., Yakovleva, M., & Donne, S. (2013). Preparation and electrochemical performance of LixMnO 2 materials by a reduction and lithiation method. Journal of The Electrochemical Society, 160(9), A1358-A1363. https://doi.org/10.1149/2.005309jes

The preparation of LixMnO2 materials via a novel reduction and lithiation method is reported. The effect of lithium concentration, lithiation temperature and lithiation time on the composition, structure and electrochemical performance of the resulti... Read More about Preparation and electrochemical performance of Li<inf>x</inf>MnO <inf>2</inf> materials by a reduction and lithiation method.

Reversible recruitment and emission of DO3A-derived lanthanide complexes at ligating molecular films on gold (2013)
Journal Article
Lehr, J., Bennett, J., Tropiano, M., Sørensen, T., Faulkner, S., Beer, P., & Davis, J. (2013). Reversible recruitment and emission of DO3A-derived lanthanide complexes at ligating molecular films on gold. Langmuir, 29(5), 1475-1482. https://doi.org/10.1021/la3046725

The recruitment of DO3A-derived lanthanide complexes by ligation to isophthalic acid and catechol-modified gold surfaces, and their resulting sensitization, is reported herein. Predictably pH-dependent surface recruitment is associated with the expec... Read More about Reversible recruitment and emission of DO3A-derived lanthanide complexes at ligating molecular films on gold.

Thermal lithiation of manganese dioxide : effect of low lithium concentration (x ≤ 0.3 in Li <inf>x</inf>MnO <inf>2</inf>) on structure and electrochemical performance (2012)
Journal Article
Lehr, J., Dose, W., Yakovleva, M., & Donne, S. (2012). Thermal lithiation of manganese dioxide : effect of low lithium concentration (x ≤ 0.3 in Li xMnO 2) on structure and electrochemical performance. Journal of The Electrochemical Society, 159(6), A904-A908. https://doi.org/10.1149/2.115206jes

The Electrochemical Society, find out more Thermal Lithiation of Manganese Dioxide: Effect of Low Lithium Concentration (x ≤ 0.3 in LixMnO2) on Structure and Electrochemical Performance Joshua Lehr1, Wesley M. Dose1, Marina Yakovleva2 and S... Read More about Thermal lithiation of manganese dioxide : effect of low lithium concentration (x ≤ 0.3 in Li <inf>x</inf>MnO <inf>2</inf>) on structure and electrochemical performance.

Characterisation of chemically lithiated heat-treated electrolytic manganese dioxide (2011)
Journal Article
Dose, W., Lehr, J., & Donne, S. (2012). Characterisation of chemically lithiated heat-treated electrolytic manganese dioxide. Materials Research Bulletin, 47(7), 1827-1834. https://doi.org/10.1016/j.materresbull.2011.05.027

Heat treated manganese dioxide is partially lithiated using butyl-lithium to determine the changes in crystal structure, chemical composition and morphology upon reduction, as a means of simulating its discharge behaviour in a non-aqueous battery cat... Read More about Characterisation of chemically lithiated heat-treated electrolytic manganese dioxide.

Spontaneous grafting of nitrophenyl groups to planar glassy carbon substrates : evidence for two mechanisms (2011)
Journal Article
Lehr, J., Williamson, B., & Downard, A. (2011). Spontaneous grafting of nitrophenyl groups to planar glassy carbon substrates : evidence for two mechanisms. Journal of Physical Chemistry C, 115(14), 6629-6634. https://doi.org/10.1021/jp111838r

The covalent grafting of nitrophenyl functionalities to planar carbon substrates by reaction with 4-nitrobenezene diazonium salt at open circuit potential has been studied in aqueous acid and acetonitrile solutions. Atomic force microscopy and electr... Read More about Spontaneous grafting of nitrophenyl groups to planar glassy carbon substrates : evidence for two mechanisms.

Patterning of metal, carbon, and semiconductor substrates with thin organic films by microcontact printing with aryldiazonium salt inks (2010)
Journal Article
Lehr, J., Garrett, D., Paulik, M., Flavel, B., Brooksby, P., Williamson, B., & Downard, A. (2010). Patterning of metal, carbon, and semiconductor substrates with thin organic films by microcontact printing with aryldiazonium salt inks. Analytical Chemistry, 82(16), 7027-7034. https://doi.org/10.1021/ac101785c

Surface modification through reduction of aryldiazonium salts to give covalently attached layers is a widely investigated procedure. However, realization of potential applications of the layers requires development of patterning methods. Here, we dem... Read More about Patterning of metal, carbon, and semiconductor substrates with thin organic films by microcontact printing with aryldiazonium salt inks.

Chemically immobilised carbon nanotubes on silicon : stable surfaces for aqueous electrochemistry (2010)
Journal Article
Flavel, B., Garrett, D., Lehr, J., Shapter, J., & Downard, A. (2010). Chemically immobilised carbon nanotubes on silicon : stable surfaces for aqueous electrochemistry. Electrochimica Acta, 55(12), 3995-4001. https://doi.org/10.1016/j.electacta.2010.02.046

Diazonium ion chemistry has been used to electrochemically graft aminophenyl layers onto p-type silicon (1 0 0) substrates. A condensation reaction was used to immobilise single-walled carbon nanotubes with high carboxylic acid functionality directly... Read More about Chemically immobilised carbon nanotubes on silicon : stable surfaces for aqueous electrochemistry.

Dependence of catalytic activity and long-term stability of enzyme hydrogel films on curing time (2009)
Journal Article
Lehr, J., Williamson, B., Barrière, F., & Downard, A. (2010). Dependence of catalytic activity and long-term stability of enzyme hydrogel films on curing time. Bioelectrochemistry, 79(1), 142-146. https://doi.org/10.1016/j.bioelechem.2009.12.004

Enzyme hydrogels were prepared on carbon film electrodes using glucose oxidase and an epoxide crosslinking agent. The catalytic activity of the gels was found to depend strongly on curing time. The competing effects of increased mechanical stability... Read More about Dependence of catalytic activity and long-term stability of enzyme hydrogel films on curing time.

Reaction of gold substrates with diazonium salts in acidic solution at open-circuit potential (2009)
Journal Article
Lehr, J., Williamson, B., Flavel, B., & Downard, A. (2009). Reaction of gold substrates with diazonium salts in acidic solution at open-circuit potential. Langmuir, 25(23), 13503-13509. https://doi.org/10.1021/la902002n

The reaction of gold substrates with p-nitrobenzene diazonium tetrafluoroborate (NBD) in 0.1 M H2SO4 at open-circuit potential (OCP) is demonstrated to proceed by electron transfer from gold to the NBD cation. Electrochemical, atomic force microscopy... Read More about Reaction of gold substrates with diazonium salts in acidic solution at open-circuit potential.

Microcontact printing using the spontaneous reduction of aryldiazonium salts (2007)
Journal Article
Garrett, D., Lehr, J., Miskelly, G., & Downard, A. (2007). Microcontact printing using the spontaneous reduction of aryldiazonium salts. Abstracts of papers / American Chemical Society, 129(50), 15456-15457. https://doi.org/10.1021/ja0775321

Patterning of aryl derivatives on graphitic carbon surfaces by printing with poly(dimethylsiloxane) stamps is described. The printing ink contained aryldiazonium salts which react spontaneously with the carbon substrate (pyrolyzed photoresist film) r... Read More about Microcontact printing using the spontaneous reduction of aryldiazonium salts.