Analogues of Y27632 increase gap junction communication and suppress the formation of transformed NIH3T3 colonies

Hampson, Lynne; He, X; Hadfield, JA; Kemp, T; Butler, J; Mcgown, A; Kitchener, H; Hampson, I

doi:10.1038/sj.bjc.6605208

Constitutive activation of RhoA-dependent RhoA kinase (ROCK) signalling is known to promote cellular transformation and the ROCK inhibitor Y-27632 has the ability to suppress focus formation of RhoA transformed NIH3T3 cells. METHODS: Sixty-four novel... Read More about Analogues of Y27632 increase gap junction communication and suppress the formation of transformed NIH3T3 colonies.

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