All Outputs (3)

Mathematical models of DNA methylation dynamics: Implications for health and ageing (2018)
Journal Article

DNA methylation is a key epigenetic process which has been intimately associated with gene regulation. In recent years growing evidence has associated DNA methylation status with a variety of diseases including cancer, Alzheimer’s disease and cardiov... Read More about Mathematical models of DNA methylation dynamics: Implications for health and ageing.

Disrupting folate metabolism reduces the capacity of bacteria in exponential growth to develop persisters to antibiotics (2018)
Journal Article

Bacteria can survive high doses of antibiotics through stochastic phenotypic diversification. We present initial evidence that folate metabolism could be involved with the formation of persisters. The aberrant expression of the folate enzyme gene fau... Read More about Disrupting folate metabolism reduces the capacity of bacteria in exponential growth to develop persisters to antibiotics.

The role of DNA methylation in ageing and cancer (2018)
Journal Article
Morgan, A. E., Davies, T. J., & Mc Auley, M. T. (2018). The role of DNA methylation in ageing and cancer. Proceedings of the Nutrition Society, 77(4), 412-422. https://doi.org/10.1017/S0029665118000150

The aim of the present review paper is to survey the literature related to DNA methylation, and its association with cancer and ageing. The review will outline the key factors, including diet, which modulate DNA methylation. Our rationale for conduct... Read More about The role of DNA methylation in ageing and cancer.