Skip to main content

Research Repository

Advanced Search

All Outputs (12)

Identification of constrained sequence elements across 239 primate genomes. (2023)
Journal Article
Kuderna, L. F., Ulirsch, J. C., Rashid, S., Ameen, M., Sundaram, L., Hickey, G., …Farh, K. K. (2023). Identification of constrained sequence elements across 239 primate genomes. Nature, 36, https://doi.org/10.1038/s41586-023-06798-8

Noncoding DNA is central to our understanding of human gene regulation and complex diseases , and measuring the evolutionary sequence constraint can establish the functional relevance of putative regulatory elements in the human genome . Identifying... Read More about Identification of constrained sequence elements across 239 primate genomes..

Complex Evolutionary History With Extensive Ancestral Gene Flow in an African Primate Radiation (2023)
Journal Article
Jensen, A., Swift, F., de Vries, D., Beck, R. M. D., Kuderna, L. F. K., Knauf, S., …Guschanski, K. (2023). Complex Evolutionary History With Extensive Ancestral Gene Flow in an African Primate Radiation. Molecular Biology and Evolution, 40(12), https://doi.org/10.1093/molbev/msad247

Understanding the drivers of speciation is fundamental in evolutionary biology, and recent studies highlight hybridization as an important evolutionary force. Using whole-genome sequencing data from 22 species of guenons (tribe Cercopithecini), one o... Read More about Complex Evolutionary History With Extensive Ancestral Gene Flow in an African Primate Radiation.

Complex evolutionary history with extensive ancestral gene flow in an African primate radiation (2023)
Journal Article
Jensen, A., Swift, F., de Vries, D., Beck, R., Kuderna, L. F. K., Knauf, S., …Guschanski, K. (in press). Complex evolutionary history with extensive ancestral gene flow in an African primate radiation. Molecular Biology and Evolution, 40(12), https://doi.org/10.1093/molbev/msad247

Understanding the drivers of speciation is fundamental in evolutionary biology, and recent studies highlight hybridization as an important evolutionary force. Using whole-genome sequencing data from 22 species of guenons (tribe Cercopithecini), one o... Read More about Complex evolutionary history with extensive ancestral gene flow in an African primate radiation.

The landscape of tolerated genetic variation in humans and primates. (2023)
Journal Article
Gao, H., Hamp, T., Ede, J., Schraiber, J. G., McRae, J., Singer-Berk, M., …Jolly, C. J. (2023). The landscape of tolerated genetic variation in humans and primates. Science, 380(6648), https://doi.org/10.1126/science.abn8197

Personalized genome sequencing has revealed millions of genetic differences between individuals, but our understanding of their clinical relevance remains largely incomplete. To systematically decipher the effects of human genetic variants, we obtain... Read More about The landscape of tolerated genetic variation in humans and primates..

A global catalog of whole-genome diversity from 233 primate species. (2023)
Journal Article
Kuderna, L. F. K., Gao, H., Janiak, M. C., Kuhlwilm, M., Orkin, J. D., Bataillon, T., …Jolly, C. J. (2023). A global catalog of whole-genome diversity from 233 primate species. Science, 380(6648), 906-913. https://doi.org/10.1126/science.abn7829

The rich diversity of morphology and behavior displayed across primate species provides an informative context in which to study the impact of genomic diversity on fundamental biological processes. Analysis of that diversity provides insight into lon... Read More about A global catalog of whole-genome diversity from 233 primate species..

Twenty-five well-justified fossil calibrations for primate divergences (2023)
Journal Article
de Vries, D., & Beck, R. M. D. (2023). Twenty-five well-justified fossil calibrations for primate divergences. #Journal not on list, 26(1), https://doi.org/10.26879/1249

Phylogenies with estimates of divergence times are essential for investigating many evolutionary questions. In principle, “tip-dating” is arguably the most appropriate approach, with fossil and extant taxa analysed together in a single analysis, and... Read More about Twenty-five well-justified fossil calibrations for primate divergences.

Two hundred and five newly assembled mitogenomes provide mixed evidence for rivers as drivers of speciation for Amazonian primates (2022)
Journal Article
Janiak, M. C., Silva, F. E., Beck, R. M. D., de Vries, D., Kuderna, L. F. K., Torosin, N. S., …Boubli, J. P. (2022). Two hundred and five newly assembled mitogenomes provide mixed evidence for rivers as drivers of speciation for Amazonian primates. Molecular Ecology, 31(14), 3888-3902. https://doi.org/10.1111/mec.16554

Mitochondrial DNA remains a cornerstone for molecular ecology, especially for study species from which high-quality tissue samples cannot be easily obtained. Methods using mitochondrial markers are usually reliant on reference databases, but these ar... Read More about Two hundred and five newly assembled mitogenomes provide mixed evidence for rivers as drivers of speciation for Amazonian primates.

New phiocricetomyine rodents (Hystricognathi) from the Jebel Qatrani Formation, Fayum Depression, Egypt (2021)
Journal Article
Al-Ashqar, S., Seiffert, E., de Vries, D., El-Sayed, S., Antar, M., & Sallam, H. (2021). New phiocricetomyine rodents (Hystricognathi) from the Jebel Qatrani Formation, Fayum Depression, Egypt. PeerJ, 9, e12074. https://doi.org/10.7717/peerj.12074

Background The rich rodent assemblages from the Eocene–Oligocene deposits of the Jebel Qatrani Formation (Fayum Depression, Egypt) have important implications for our understanding of the origin and paleobiogeography of Hystricognathi, a diverse clad... Read More about New phiocricetomyine rodents (Hystricognathi) from the Jebel Qatrani Formation, Fayum Depression, Egypt.

Ancient DNA of the pygmy marmoset type specimen Cebuella pygmaea (Spix, 1823) resolves a taxonomic conundrum (2021)
Journal Article
Boubli, J., Janiak, M., Porter, L., de la Torre, S., Cortés-Ortiz, L., da Silva, M., …Roos, C. (2021). Ancient DNA of the pygmy marmoset type specimen Cebuella pygmaea (Spix, 1823) resolves a taxonomic conundrum. Zoological Research, 42(6), 761-771. https://doi.org/10.24272/j.issn.2095-8137.2021.143

The pygmy marmoset, the smallest of the anthropoid primates, has a broad distribution in Western Amazonia. Recent studies using molecular and morphological data have identified two distinct species separated by the Napo and Solimões-Amazonas rivers.... Read More about Ancient DNA of the pygmy marmoset type specimen Cebuella pygmaea (Spix, 1823) resolves a taxonomic conundrum.

Widespread loss of mammalian lineage and dietary diversity in the early Oligocene of Afro-Arabia (2021)
Journal Article
de Vries, D., Heritage, S., Borths, M., Sallam, H., & Seiffert, E. (2021). Widespread loss of mammalian lineage and dietary diversity in the early Oligocene of Afro-Arabia. Communications Biology, 4(1), 1172. https://doi.org/10.1038/s42003-021-02707-9

Diverse lines of geological and geochemical evidence indicate that the Eocene-Oligocene transition (EOT) marked the onset of a global cooling phase, rapid growth of the Antarctic ice sheet, and a worldwide drop in sea level. Paleontologists have esta... Read More about Widespread loss of mammalian lineage and dietary diversity in the early Oligocene of Afro-Arabia.

An early Oligocene age for the oldest known monkeys and rodents of South America (2021)
Journal Article
Campbell, K., O'Sullivan, P., Fleagle, J., de Vries, D., & Seiffert, E. (2021). An early Oligocene age for the oldest known monkeys and rodents of South America. Proceedings of the National Academy of Sciences, 118(37), e2105956118. https://doi.org/10.1073/pnas.2105956118

The Santa Rosa fossil locality in eastern Perú produced the first Paleogene vertebrate fauna from the Amazon Basin, including the oldest known monkeys from South America. This diverse paleofauna was originally assigned an Eocene age based largely on... Read More about An early Oligocene age for the oldest known monkeys and rodents of South America.

The evolution of mammalian brain size (2021)
Journal Article
Smaers, J., Rothman, R., Hudson, D., Balanoff, A., Beatty, B., Dechmann, D., …Safi, K. (2021). The evolution of mammalian brain size. Science Advances, 7(18), eabe2101. https://doi.org/10.1126/sciadv.abe2101

Relative brain size has long been considered a reflection of cognitive capacities and has played a fundamental role in developing core theories in the life sciences. Yet, the notion that relative brain size validly represents selection on brain size... Read More about The evolution of mammalian brain size.