Novel heparin mimics as inhibitors of HGF-induced activation of Met : design, synthesis and biological evaluation
(2010)
Thesis
Lagoutte, R. Novel heparin mimics as inhibitors of HGF-induced activation of Met : design, synthesis and biological evaluation. (Thesis). Salford : University of Salford
In chapter one, hepatocyte growth factor HGF, its receptor, the tyrosine kinase Met and their biological implications are introduced, and the structure and role of the glycosaminoglycans (GAGs) heparan sulfate and heparin are described. An account... Read More about Novel heparin mimics as inhibitors of HGF-induced activation of Met : design, synthesis and biological evaluation.