All Outputs (2)

Validation of shellfish isolates (glycosaminoglycans, GAGs) for development as a novel anti-tumour therapy for children : GAG action on lymphocytes/T-regulatory cells
Thesis
Jones, C. Validation of shellfish isolates (glycosaminoglycans, GAGs) for development as a novel anti-tumour therapy for children : GAG action on lymphocytes/T-regulatory cells. (Thesis). University of Salford

Introduction: Leukaemia is cancer of white blood cells (WBCs) mainly affecting children. Defective WBCs are prominent in blood and cannot provide immune protection. Although chemotherapy treatments are effective, they have many adverse effects which... Read More about Validation of shellfish isolates (glycosaminoglycans, GAGs) for development as a novel anti-tumour therapy for children : GAG action on lymphocytes/T-regulatory cells.

Molecular pathways controlling DNA damage response
Thesis
Alhebshi, H. (in press). Molecular pathways controlling DNA damage response. (Thesis). University of Salford

P53 is inactivated in around 50 % of human neoplasms and more than 26,000 somatic mutations of the p53 have reported in human cancers. P53 network is activated after cells are exposed to the DNA damage and depending on diverse conditions and type of... Read More about Molecular pathways controlling DNA damage response.