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All Outputs (3)

The role of the human endonuclease VIII-like 1 and 3 in the repair of DNA replication blocking lesions
Thesis
Martin, P. (in press). The role of the human endonuclease VIII-like 1 and 3 in the repair of DNA replication blocking lesions. (Thesis). University of Salford

The endonuclease VIII family of DNA glycosylases initiate repair of oxidative DNA base damage through BER and have been shown to resolve DNA inter-strand crosslinks (ICLs), arising from exogenous agents. Human NEIL1 (hNEIL1) activity on psoralen gene... Read More about The role of the human endonuclease VIII-like 1 and 3 in the repair of DNA replication blocking lesions.

Regulation of autophagy, endoplasmic reticulum and unfolded protein response by glucocorticoids in physiology and disease
Thesis
Sudsaward, S. (in press). Regulation of autophagy, endoplasmic reticulum and unfolded protein response by glucocorticoids in physiology and disease. (Thesis). University of Salford

Acute lymphoblastic leukemia (ALL) is the most frequent cancer in children, and although highly treatable, challenges remain due to significant side effects of therapy and the poor outcome for some patients. Synthetic glucocorticoid, Dexamethasone (D... Read More about Regulation of autophagy, endoplasmic reticulum and unfolded protein response by glucocorticoids in physiology and disease.