Outputs (26)

Harnessing the Power of MicroRNA Cargoes in Small Extracellular Vesicles Released from Fresh-Frozen Human Brain Sections (2024)
Journal Article

Small extracellular vesicles (sEVs) are crucial mediators of cell-cell communication, transporting diverse cargoes like proteins, lipids, and nucleic acids (microRNA, mRNA, DNA). The microRNA sEV cargo has potential utility as a powerful non-invasive... Read More about Harnessing the Power of MicroRNA Cargoes in Small Extracellular Vesicles Released from Fresh-Frozen Human Brain Sections.

In vitro and in vivo evaluation of the effect of Aspergillus fumigatus on epithelial cells. (2024)
Thesis

Aspergillus fumigatus is a saprophytic fungus and one of the most prevalent airborne pathogens. Asthma is severe and associated with increased mortality in those patients that have fungal sensitisation. Mechanisms of airway wall remodelling and the p... Read More about In vitro and in vivo evaluation of the effect of Aspergillus fumigatus on epithelial cells..

Evaluating the Impact of E-Liquids on Small Extracellular Vesicles Released from Three-Dimensional Cell Culture of Human Lung Cells (2024)
Thesis

Small Extracellular Vesicles (sEVs), membrane-bound vesicles used in cellular communication can be used as a source of biomarkers for lung damage and disease, to minimise need for invasive test procedures. E-cigarette use has grown in recent years, b... Read More about Evaluating the Impact of E-Liquids on Small Extracellular Vesicles Released from Three-Dimensional Cell Culture of Human Lung Cells.

The Theranostic Role of Small Extracellular Vesicle Mediated microRNA in Medulloblastoma (2024)
Thesis

Small extracellular vesicles (sEVs) cargo can potentially alter response to chemotherapy, indicating specific cargo as a potential theranostic biomarker. In this study, we explored miRNAs mediated sEVs for chemotherapy associated biomarkers. We took... Read More about The Theranostic Role of Small Extracellular Vesicle Mediated microRNA in Medulloblastoma.

De novo copy number variations in candidate genomic regions in patients of severe autism spectrum disorder in Vietnam (2024)
Journal Article

Autism spectrum disorder (ASD) is a developmental disorder with a prevalence of around 1% children worldwide and characterized by patient behaviour (communication, social interaction, and personal development). Data on the efficacy of diagnostic test... Read More about De novo copy number variations in candidate genomic regions in patients of severe autism spectrum disorder in Vietnam.

Film storytelling can enhance learning in STEM subjects (2024)
Digital Artefact
Mukhopadhyay, A. Film storytelling can enhance learning in STEM subjects. [Online]

Investigating small extracellular vesicle miRNA as biomarkers for Alzheimer’s disease (2023)
Thesis

Alzheimer’s disease (AD) is the leading cause of dementia, a syndrome impacting over 900,000 people in the UK alone. There are currently no disease modifying treatments for AD, which is largely attributable to the heterogenous basis of the disease wh... Read More about Investigating small extracellular vesicle miRNA as biomarkers for Alzheimer’s disease.

Whole exome sequencing reveals novel candidate genes in familial forms of Glaucomatous Neurodegeneration (2023)
Journal Article

Glaucoma is the largest cause of irreversible blindness with a multifactorial genetic etiology. This study explores novel genes and gene networks in familial forms of primary open angle glaucoma (POAG) and primary angle closure glaucoma (PACG) to ide... Read More about Whole exome sequencing reveals novel candidate genes in familial forms of Glaucomatous Neurodegeneration.

Whole exome-sequencing of vitiligo lesions indicate lower burden of somatic variations: implications in risk for non-melanoma skin cancers (2022)
Journal Article

Genetic depigmentary conditions such as albinism with complete loss of epidermal pigmentation pose a higher risk for cutaneous malignancies ( Lekalakala et al., 2015 ). By analogy, clinical management for photoprotection of the acquired depigmented s... Read More about Whole exome-sequencing of vitiligo lesions indicate lower burden of somatic variations: implications in risk for non-melanoma skin cancers.

Evaluation of small extracellular vesicular microRNAs as biomarkers for exposure of nicotine and E-liquids on human lung cells (2022)
Thesis
for exposure of nicotine and E-liquids on human lung cells. (Thesis). University of Salford

Nicotine intake and E-Cigarette or vaping product use-associated lung injury (EVALI) can cause pulmonary disease with damaging health effects. In this study, we explored miRNAs from small extracellular vesicles (sEVs) for nicotine and E-liquid-associ... Read More about Evaluation of small extracellular vesicular microRNAs as biomarkers for exposure of nicotine and E-liquids on human lung cells.