Outputs (62)

Calcium signaling in endothelial and vascular smooth muscle cells: sex differences and the influence of estrogens and androgens (2024)
Journal Article
Asunción-Alvarez, D., Palacios, J., Ybañez-Julca, R. O., Rodriguez-Silva, C. N., Nwokocha, C., Cifuentes, F., & Greensmith, D. J. (2024). Calcium signaling in endothelial and vascular smooth muscle cells: sex differences and the influence of estrogens and androgens. American journal of physiology. Heart and circulatory physiology, 326(4), H950-H970. https://doi.org/10.1152/ajpheart.00600.2023

Calcium signaling in vascular endothelial cells (ECs) and smooth muscle cells (VSMCs) is essential for the regulation of vascular tone. However, the changes to intracellular Ca2+ concentrations are often influenced by sex differences. Furthermore, a... Read More about Calcium signaling in endothelial and vascular smooth muscle cells: sex differences and the influence of estrogens and androgens.

The role of interleukin-10 in coronary artery disease (2023)
Thesis

Coronary artery disease (CAD) is a leading cause of mortality and morbidity worldwide, accounting for 66,000 deaths annually in the UK. Atherosclerosis is the underlying pathophysiological mechanism which drives CAD progression, producing an inflamma... Read More about The role of interleukin-10 in coronary artery disease.

The effects of doxorubicin on calcium handling and contractility in sheep ventricular myocytes; role of oxidative stress (2023)
Presentation / Conference Contribution

Anthracyclines such as doxorubicin (DOX) are effective chemotherapeutics and contribute to improved cancer survival rates in children and adults. However, anthracyclines exhibit acute and chronic cardiotoxicity which can produce heart failure in canc... Read More about The effects of doxorubicin on calcium handling and contractility in sheep ventricular myocytes; role of oxidative stress.

The effects of anthracyclines on calcium handling and contractility in sheep ventricular myocytes; role of oxidative stress (2023)
Thesis

Anthracyclines such as doxorubicin (DOX) and daunorubicin (DAUN) are effective chemotherapeutics and contribute to improved cancer survival rates in children and adults. However, anthracyclines exhibit acute and chronic cardiotoxicity which can produ... Read More about The effects of anthracyclines on calcium handling and contractility in sheep ventricular myocytes; role of oxidative stress.

The effects of Senecio nutans hydroalcoholic extract on cardiac function (2023)
Presentation / Conference
Jones, M. (2023, May). The effects of Senecio nutans hydroalcoholic extract on cardiac function. Presented at Greater Manchester Physiology Symposium 2023, University of Salford

Enhancing employability through building graduate capital: a multi-faceted approach (2023)
Report
capital: a multi-faceted approach

The University of Salford is home to a diverse community of learners, a high proportion of whom are
from underprivileged socioeconomic backgrounds and/or underrepresented communities and many
are commuters. A significant proportion of the cohort ga... Read More about Enhancing employability through building graduate capital: a multi-faceted approach.

Characterisation of inflammatory mediators in ischaemic heart disease (2022)
Thesis
Borun, A. Characterisation of inflammatory mediators in ischaemic heart disease. (Dissertation). University of Salford

Coronary artery disease (CAD) is one of the most common causes of death in general population. In the UK it accounts for 64000 deaths annually and there are currently 2.3 million people living with CAD. Persistent inflammation of myocardium is believ... Read More about Characterisation of inflammatory mediators in ischaemic heart disease.

Characterisation of inflammatory mediators in ischaemic heart disease (2022)
Thesis
Borun, A. Characterisation of inflammatory mediators in ischaemic heart disease. (Dissertation). University of Salford

Coronary artery disease (CAD) is one of the most common causes of death in general population. In the UK it accounts for 64000 deaths annually and there are currently 2.3 million people living with CAD. Persistent inflammation of myocardium is believ... Read More about Characterisation of inflammatory mediators in ischaemic heart disease.

The role of serum biomarkers and oxidative stress in Ischemic Heart Disease (2022)
Thesis
Riley, C. The role of serum biomarkers and oxidative stress in Ischemic Heart Disease. (Dissertation). University of Salford

Ischemic heart disease also referred to as coronary artery disease (CAD) is a leading cause of death worldwide. The primary pathological mechanism underlying CAD is atherosclerosis, an inflammatory process associated with an accumulation of lipids an... Read More about The role of serum biomarkers and oxidative stress in Ischemic Heart Disease.

A hydroalcoholic extract of Senecio nutans SCh. Bip (Asteraceae); its effects on cardiac function and chemical characterization (2022)
Journal Article

Ethnopharmacology relevance
The plant Senecio nutans SCh. Bip. is used by Andean communities to treat altitude sickness. Recent evidence suggests it may produce vasodilation and negative cardiac inotropy, though the cellular mechanisms have not been... Read More about A hydroalcoholic extract of Senecio nutans SCh. Bip (Asteraceae); its effects on cardiac function and chemical characterization.