The role of the anaesthetised guinea-pig in the preclinical cardiac safety evaluation of drug candidate compounds
(2012)
Journal Article
Despite rigorous preclinical and clinical safety evaluation, adverse cardiac effects remain a leading cause of drug attrition and post-approval drug withdrawal. A number of cardiovascular screens exist within preclinical development. These screens do... Read More about The role of the anaesthetised guinea-pig in the preclinical cardiac safety evaluation of drug candidate compounds.