Outputs (6)

Systems analysis of the liver transcriptome in adult male zebrafish exposed to the non-ionic surfactant nonylphenol (2018)
Journal Article
Huff, M., Abraham da Silveira, W., Starr Hazard, E., Courtney, S. M., Renaud, L., & Hardiman, G. (2019). Systems analysis of the liver transcriptome in adult male zebrafish exposed to the non-ionic surfactant nonylphenol. General and Comparative Endocrinology, 271, 1-14. https://doi.org/10.1016/j.ygcen.2018.10.016

Nonylphenol (NP) arises from the environmental degradation of nonylphenol ethoxylates. It is a ubiquitous environmental contaminant and has been detected at levels up to 167 nM in rivers in the United States. NP is an endocrine disruptor (ED) that ca... Read More about Systems analysis of the liver transcriptome in adult male zebrafish exposed to the non-ionic surfactant nonylphenol.

Identification of a Subtype of Poorly Differentiated Invasive Ductal Carcinoma of the Breast Based on Vimentin and E-cadherin Expression (2018)
Journal Article

Objective: The use of molecular markers can identify a subgroup of tumors with distinct recurrence patterns. The present study aimed to characterize the immunohistochemical expression of vimentin (VIM), of E-cadherin (CDH1), and of cytokeratin 5 (CK5... Read More about Identification of a Subtype of Poorly Differentiated Invasive Ductal Carcinoma of the Breast Based on Vimentin and E-cadherin Expression.

miRmapper: A Tool for Interpretation of miRNA–mRNA Interaction Networks (2018)
Journal Article
Da Silveira, W. A., Renaud, L., Simpson, J., Glen, W. B., Hazard, E. S., Chung, D., & Hardiman, G. (2018). miRmapper: A Tool for Interpretation of miRNA–mRNA Interaction Networks. Genes, 9(9), Article 458. https://doi.org/10.3390/genes9090458

It is estimated that 30% of all genes in the mammalian cells are regulated by microRNA (miRNAs). The most relevant miRNAs in a cellular context are not necessarily those with the greatest change in expression levels between healthy and diseased tissu... Read More about miRmapper: A Tool for Interpretation of miRNA–mRNA Interaction Networks.

Interplay Between MicroRNAs and Targeted Genes in Cellular Homeostasis of Adult Zebrafish (Danio rerio) (2018)
Journal Article
Renaud, L., da Silveira, W. A., Glen, W. B., Hazard, E. S., & Hardiman, G. (2018). Interplay Between MicroRNAs and Targeted Genes in Cellular Homeostasis of Adult Zebrafish (Danio rerio). Current Genomics, 19(7), 615-629. https://doi.org/10.2174/1389202919666180503124522

Background: Cellular homeostasis is regulated by the intricate interplay between a plethora of signaling pathways and "energetic sensors" in organs. In order to maintain energy balance, induction or repression of metabolic pathways must be regulated... Read More about Interplay Between MicroRNAs and Targeted Genes in Cellular Homeostasis of Adult Zebrafish (Danio rerio).

Systems Analysis of the Liver Transcriptome in Adult Male Zebrafish Exposed to the Plasticizer (2-Ethylhexyl) Phthalate (DEHP) (2018)
Journal Article
Huff, M., Carnevali, O., da Silveira, W. A., Renaud, L., & Hardiman, G. (2018). Systems Analysis of the Liver Transcriptome in Adult Male Zebrafish Exposed to the Plasticizer (2-Ethylhexyl) Phthalate (DEHP). Scientific reports, 8, Article 2118. https://doi.org/10.1038/s41598-018-20266-8

The organic compound diethylhexyl phthalate (DEHP) represents a high production volume chemical found in cosmetics, personal care products, laundry detergents, and household items. DEHP, along with other phthalates causes endocrine disruption in male... Read More about Systems Analysis of the Liver Transcriptome in Adult Male Zebrafish Exposed to the Plasticizer (2-Ethylhexyl) Phthalate (DEHP).

Semi-supervised identification of cancer subgroups using survival outcomes and overlapping grouping information (2018)
Journal Article

Identification of cancer patient subgroups using high throughput genomic data is of critical importance to clinicians and scientists because it can offer opportunities for more personalized treatment and overlapping treatments of cancers. In spite of... Read More about Semi-supervised identification of cancer subgroups using survival outcomes and overlapping grouping information.