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Outputs (629)

Targeting cancer stem cell propagation with palbociclib, a CDK4/6 inhibitor: Telomerase drives tumor cell heterogeneity (2016)
Journal Article
Bonuccelli, G., Peires-Pages, M., Ozsvari, B., Martinez- Outschoorn, U., Sotgia, F., & Lisanti, M. (2017). Targeting cancer stem cell propagation with palbociclib, a CDK4/6 inhibitor: Telomerase drives tumor cell heterogeneity. Oncotarget, 8(6), 9868-9884. https://doi.org/10.18632/oncotarget.14196

In this report, we systematically examined the role of telomerase activity in
lung and ovarian cancer stem cell (CSC) propagation. For this purpose, we indirectly
gauged telomerase activity, by linking the hTERT-promoter to eGFP. Using lung
(A549)... Read More about Targeting cancer stem cell propagation with palbociclib, a CDK4/6 inhibitor: Telomerase drives tumor cell heterogeneity.

Heat-flow variability of suspended timber ground floors: Implications for in-situ heat-flux measuring (2016)
Journal Article

Reducing space heating energy demand supports the UK’s legislated carbon emission reduction targets and requires the effective characterisation of the UK’s existing housing stock to facilitate retrofitting decision-making. Approximately 6.6 million U... Read More about Heat-flow variability of suspended timber ground floors: Implications for in-situ heat-flux measuring.

Numerical study of slip effects on unsteady aysmmetric bioconvective nanofluid flow in a porous microchannel with an expanding/ contracting upper wall using Buongiorno’s model (2016)
Journal Article
Beg, O., Basir, M., Uddin, M., & Ismail, A. (2016). Numerical study of slip effects on unsteady aysmmetric bioconvective nanofluid flow in a porous microchannel with an expanding/ contracting upper wall using Buongiorno’s model. Journal of Mechanics in Medicine and Biology, 17(3), 1750059. https://doi.org/10.1142/S0219519417500592

In this paper, the unsteady fully developed forced convective flow of viscous incompressible biofluid that contains both nanoparticles and gyrotactic microorganisms in a horizontal micro-channel is studied. Buongiorno’s model is employed. The upper c... Read More about Numerical study of slip effects on unsteady aysmmetric bioconvective nanofluid flow in a porous microchannel with an expanding/ contracting upper wall using Buongiorno’s model.

Human commercial models’ eye colour shows negative frequency-dependent selection (2016)
Journal Article
frequency-dependent selection. PLoS ONE, 11(12), e0168458. https://doi.org/10.1371/journal.pone.0168458

In this study we investigated the eye colour of human commercial models registered in the UK (400 female and 400 male) and Brazil (400 female and 400 male) to test the hypothesis that model eye colour frequency was the result of negative frequency de... Read More about Human commercial models’ eye colour shows negative frequency-dependent selection.

Computational modelling folate metabolism and DNA methylation: implications for understanding health and ageing (2016)
Journal Article

Dietary folates have a key role to play in health, as deficiencies in the intake of these B vitamins have been implicated in a wide variety of clinical conditions. The reason for this is folates function as single carbon donors in the synthesis of me... Read More about Computational modelling folate metabolism and DNA methylation: implications for understanding health and ageing.

Spatio-temporal monitoring of deep-sea communities using metabarcoding of sediment DNA and RNA (2016)
Journal Article
Guardiola, M., Wangensteen Fuentes, O., Taberlet, P., Coissac, E., Uriz, M., & Turon, X. (2016). Spatio-temporal monitoring of deep-sea communities using metabarcoding of sediment DNA and RNA. PeerJ, 4, e2807. https://doi.org/10.7717/peerj.2807

We assessed spatio-temporal patterns of diversity in deep-sea sediment communities using metabarcoding. We chose a recently developed eukaryotic marker based on the v7 region of the 18S rRNA gene. Our study was performed in a submarine canyon and its... Read More about Spatio-temporal monitoring of deep-sea communities using metabarcoding of sediment DNA and RNA.

Characterization of acoustic diffusion using refracto-vibrometry (2016)
Journal Article
Jackett, R., Piper, B., & Hughes, R. (2017). Characterization of acoustic diffusion using refracto-vibrometry. Journal of Sound and Vibration, 392, 70-76. https://doi.org/10.1016/j.jsv.2016.12.028

Refracto-vibrometry is a relatively new measurement technique that is sensitive to variations in the optical refractive index of a medium caused by changes in acoustic pressure within that medium (the acousto-optic effect). It has so far been employe... Read More about Characterization of acoustic diffusion using refracto-vibrometry.

Between the Balkans and the Baltic : phylogeography of a common vole mitochondrial DNA lineage limited to Central Europe (2016)
Journal Article

The common vole (Microtus arvalis) has been a model species of small mammal for studying
end-glacial colonization history. In the present study we expanded the sampling from
central and eastern Europe, analyzing contemporary genetic structure to id... Read More about Between the Balkans and the Baltic : phylogeography of a common vole mitochondrial DNA lineage limited to Central Europe.

Wear rate-state interaction modelling for a multi-component system : models and an experimental platform (2016)
Journal Article
Assaf, R., Scarf, P., Nefti-Meziani, S., & Do, P. (2016). Wear rate-state interaction modelling for a multi-component system : models and an experimental platform. IFAC-PapersOnLine, 49(28), 232-237. https://doi.org/10.1016/j.ifacol.2016.11.040

This paper proposes a general deterioration model for a multi-component system. The deterioration process of a component depends upon the operational conditions, the component’s own state, and also the state of other components. An experimental platf... Read More about Wear rate-state interaction modelling for a multi-component system : models and an experimental platform.