Outputs (14837)

Optimal deployment of components of cloud-hosted application for guaranteeing multitenancy isolation (2019)
Journal Article

One of the challenges of deploying multitenant cloud-hosted
services that are designed to use (or be integrated with) several
components is how to implement the required degree
of isolation between the components when there is a change
in the wor... Read More about Optimal deployment of components of cloud-hosted application for guaranteeing multitenancy isolation.

A Human Skin Model Recapitulates Systemic Sclerosis Dermal Fibrosis and Identifies COL22A1 as a TGFβ Early Response Gene that Mediates Fibroblast to Myofibroblast Transition (2019)
Journal Article
Watanabe, T., Baker Frost, D., Mlakar, L., Heywood, J., da Silveira, W. A., Hardiman, G., & Feghali-Bostwick, C. (2019). A Human Skin Model Recapitulates Systemic Sclerosis Dermal Fibrosis and Identifies COL22A1 as a TGFβ Early Response Gene that Mediates Fibroblast to Myofibroblast Transition. Genes, 10(2), Article 75. https://doi.org/10.3390/genes10020075

Systemic sclerosis (SSc) is a complex multi-system autoimmune disease characterized by immune dysregulation, vasculopathy, and organ fibrosis. Skin fibrosis causes high morbidity and impaired quality of life in affected individuals. Animal models do... Read More about A Human Skin Model Recapitulates Systemic Sclerosis Dermal Fibrosis and Identifies COL22A1 as a TGFβ Early Response Gene that Mediates Fibroblast to Myofibroblast Transition.

Lessons learnt from design, off-site construction and performance analysis of deep energy retrofit of residential buildings (2019)
Journal Article
Jankovic, L. (2019). Lessons learnt from design, off-site construction and performance analysis of deep energy retrofit of residential buildings. Energy and Buildings, 186, 319-338. https://doi.org/10.1016/j.enbuild.2019.01.011

The article introduces the process of deep energy retrofit carried out on a residential building in the UK, using a ‘TCosy’ approach in which the existing building is completely surrounded by a new thermal envelope. It reports on the entire process,... Read More about Lessons learnt from design, off-site construction and performance analysis of deep energy retrofit of residential buildings.

BAP1 status determines the sensitivity of malignant mesothelioma cells to gemcitabine treatment (2019)
Journal Article

Malignant mesothelioma (MMe) is a cancer with poor prognosis and resistance to standard treatments. Recent reports have highlighted the role of the BRCA associated protein 1 gene BAP1 in the development of MMe. In this study, the chemosensitivity of... Read More about BAP1 status determines the sensitivity of malignant mesothelioma cells to gemcitabine treatment.

Trace element uptake by herbaceous plants from the soils at a multiple trace element-contaminated site (2019)
Journal Article
Nworie, O., Qin, J., & Lin, C. (2019). Trace element uptake by herbaceous plants from the soils at a multiple trace element-contaminated site. Toxics, 7(1), 3. https://doi.org/10.3390/toxics7010003

The uptake of trace elements by wild herbaceous plants in a multiple trace element-contaminated site was investigated. The bioaccumulation factor (BF) of trace elements was markedly variable among the different plant species. On average, the BF for v... Read More about Trace element uptake by herbaceous plants from the soils at a multiple trace element-contaminated site.

Molecular Profiling of RNA Tumors Using High-Throughput RNA Sequencing: Overview of Library Preparation Methods (2019)
Book Chapter

RNA sequencing (RNA-seq) is revolutionizing the study of cancer by providing a highly sensitive and robust tool to interrogate the transcriptome. It leverages the power of deep sequencing technology and provides global and multidimensional views of t... Read More about Molecular Profiling of RNA Tumors Using High-Throughput RNA Sequencing: Overview of Library Preparation Methods.

Molecular Profiling of RNA Tumors Using High-Throughput RNA Sequencing: From Raw Data to Systems Level Analyses (2019)
Journal Article
Abraham da Silveira, W., Hazard, E. S., Chung, D., & Hardiman, G. (2019). Molecular Profiling of RNA Tumors Using High-Throughput RNA Sequencing: From Raw Data to Systems Level Analyses. Methods in Molecular Biology, 185-204. https://doi.org/10.1007/978-1-4939-9004-7_13

RNAseq is a powerful technique enabling global profiles of transcriptomes in healthy and diseased states. In this chapter we review pipelines to analyze the data generated by sequencing RNA, from raw data to a system level analysis. We first give an... Read More about Molecular Profiling of RNA Tumors Using High-Throughput RNA Sequencing: From Raw Data to Systems Level Analyses.

How Science Works KS3 (2019)
Data

CPD and curriculum resources for four videos in Youtube playlist https://youtu.be/63n8MjHLSg8

Investigations into helping asthma sufferers, practical and enquiry skills, respiration, biology.
Trying to reduce the carbon footprint of the UK music... Read More about How Science Works KS3.

Computation of entropy generation in dissipative transient natural convective viscoelastic flow (2019)
Journal Article
Kumar, M., Reddy, G., Kiran, G., Aslam, M., & Beg, O. (2019). Computation of entropy generation in dissipative transient natural convective viscoelastic flow. Heat Transfer - Asian Research, 48(3), 1067-1092. https://doi.org/10.1002/htj.21421

Entropy generation is an important aspect of modern thermal polymer processing optimization. Many polymers exhibit strongly non-Newtonian effects and dissipation effects in thermal processing. Motivated by these aspects in this article a numerical an... Read More about Computation of entropy generation in dissipative transient natural convective viscoelastic flow.

Model tests on single batter piles subjected to lateral soil movement (2019)
Journal Article
Al-Salih, O., Toma-Sabbagh, T., Alwadi, W., & Alabboodi, I. (2019). Model tests on single batter piles subjected to lateral soil movement. Research journal of applied sciences, engineering and technology (Online), 16(1), 24-29. https://doi.org/10.19026/rjaset.16.5995

A series of laboratory tests have been carried out to investigate the lateral response of battered piles under lateral soil movement. Model tests were carried out using instrumented rigid aluminium piles. The piles were embedded in homogeneous sand s... Read More about Model tests on single batter piles subjected to lateral soil movement.