Outputs (15066)

Inhibition of the platelet-derived growth factor receptor beta (PDGFRB) using gene silencing, crenolanib besylate, or imatinib mesylate hampers the malignant phenotype of mesothelioma cell lines (2017)
Journal Article

Malignant pleural mesothelioma (MPM) is a cancer of the pleural cavity resistant to chemotherapy. The identification of novel therapeutic targets is needed to improve its poor prognosis. Following a review of literature and a screening of specimens w... Read More about Inhibition of the platelet-derived growth factor receptor beta (PDGFRB) using gene silencing, crenolanib besylate, or imatinib mesylate hampers the malignant phenotype of mesothelioma cell lines.

Evolving approaches for recording the textile mill (2017)
Journal Article
Nevell, M. (2017). Evolving approaches for recording the textile mill. Industrial Archaeology Review, 38(2), 83-84. https://doi.org/10.1080/03090728.2016.1267889

This short paper notes some of the recent development s in textile mill recording in Britain focussing on developer-funded work. Targeted excavation of a mill's power systems can help to explain the site's development.

Detection of glycosylation and iron-binding protein modifications using Raman spectroscopy (2017)
Journal Article

In this study we demonstrate the use of Raman spectroscopy to determine protein modifications as a result of glycosylation and iron binding. Most proteins undergo some modifications after translation which can directly affect protein function. Identi... Read More about Detection of glycosylation and iron-binding protein modifications using Raman spectroscopy.

Capuchin monkey biogeography : understanding Sapajus Pleistocene range expansion and the current sympatry between Cebus and Sapajus (2017)
Journal Article

Aim:
Our aim was to examine gracile capuchin (Cebus) and robust capuchin monkey (Sapajus) diversification, with a focus on recent Sapajus expansion within Amazonia. We wanted to reconstruct the biogeographical history of the clade using statistical... Read More about Capuchin monkey biogeography : understanding Sapajus Pleistocene range expansion and the current sympatry between Cebus and Sapajus.

Swimming dynamics of a micro-organism in a couple stress fluid : a rheological model of embryological hydrodynamic propulsion (2017)
Journal Article
Ali, N., Sajid, M., Abbas, Z., & Beg, O. (2017). Swimming dynamics of a micro-organism in a couple stress fluid : a rheological model of embryological hydrodynamic propulsion. Journal of Mechanics in Medicine and Biology, 17(3), https://doi.org/10.1142/S0219519417500543

Mathematical simulations of embryological fluid dynamics are fundamental to improving clinical understanding of the intricate mechanisms underlying sperm locomotion. The strongly rheological nature of reproductive fluids has been established for a nu... Read More about Swimming dynamics of a micro-organism in a couple stress fluid : a rheological model of embryological hydrodynamic propulsion.

Neoadjuvant chemotherapy with trastuzumab in HER2-positive breast cancer: pathologic complete response rate, predictive and prognostic factors (2017)
Journal Article
Buzatto, I., Ribeiro-Silva, A., Andrade, J., Carrara, H., Silveira, W., & Tiezzi, D. (2017). Neoadjuvant chemotherapy with trastuzumab in HER2-positive breast cancer: pathologic complete response rate, predictive and prognostic factors. #Journal not on list, 50(2), Article e5674. https://doi.org/10.1590/1414-431x20165674

The purpose of this study was to retrospectively review the pathologic complete response (pCR) rate from patients (n=86) with stage II and III HER2-positive breast cancer treated with neoadjuvant chemotherapy at our institution from 2008 to 2013 and... Read More about Neoadjuvant chemotherapy with trastuzumab in HER2-positive breast cancer: pathologic complete response rate, predictive and prognostic factors.

Genomics pipelines and data integration: challenges and opportunities in the research setting (2017)
Journal Article

The emergence and mass utilization of high-throughput (HT) technologies, including sequencing technologies (genomics) and mass spectrometry (proteomics, metabolomics, lipids), has allowed geneticists, biologists, and biostatisticians to bridge the ga... Read More about Genomics pipelines and data integration: challenges and opportunities in the research setting.

Potential effects of rainwater-borne hydrogen peroxide on pollutants in stagnant water environments (2017)
Journal Article

Microcosm experiments were conducted to examine the effects of rainwater-borne H2O2 on inactivation of water-borne coliforms, oxidation of ammonia and nitrite, and degradation of organic pollutants in canal and urban lake water. The results show that... Read More about Potential effects of rainwater-borne hydrogen peroxide on pollutants in stagnant water environments.

Experimental study and modelling of the thermal conductivity of sandy soils of different porosities and water contents (2017)
Journal Article
and water contents. Applied Sciences, 7(2), 119. https://doi.org/10.3390/app7020119

This paper at first reports an experimental work to test the thermal conductivity of formulated sandy soil specimens of different porosities and water contents. Both needle probe and hot-plate methods were conducted and compared. It has been confirme... Read More about Experimental study and modelling of the thermal conductivity of sandy soils of different porosities and water contents.

Guanylate-binding Protein 1 (GBP1) contributes to the immunity of human mesenchymal stromal cells against toxoplasma gondii (2017)
Journal Article

Mesenchymal stromal cells (MSCs) have recently been shown to play important roles in mammalian host defenses against intracellular pathogens, but the molecular mechanism still needs to be clarified. We confirmed that human MSCs (hMSCs) pre-stimulated... Read More about Guanylate-binding Protein 1 (GBP1) contributes to the immunity of human mesenchymal stromal cells against toxoplasma gondii.