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Editorial: metabolic reprogramming in breast cancer

Scatena, C; Naccarato, AG; Ozsvari, B; Scumaci, D

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Authors

C Scatena

AG Naccarato

B Ozsvari

D Scumaci



Abstract

Metabolic reprogramming is an emerging hallmark of breast cancer. A common characteristic of tumor cells is the ability to obtain nutrients from a nutrient-deprived environment and to use them to sustain cancer progression, within crucial metabolic pathways including altered metabolism of glucose, lipids, and amino acids. Also, altered metabolism has been recognized as one of the major mechanisms of resistance to therapies. Important advances have been made to elucidate key mechanisms of metabolic reprogramming which will make possible novel strategies for overcoming breast cancer. However, for metabolic therapy to be effective there is a need to clearly understand the metabolic underpinnings of the different subtypes of breast cancer as well as the role the standard-of-care therapies play in targeting the metabolic phenotype.

Citation

Scatena, C., Naccarato, A., Ozsvari, B., & Scumaci, D. (2022). Editorial: metabolic reprogramming in breast cancer. Frontiers in Oncology, 12, https://doi.org/10.3389/fonc.2022.1081171

Journal Article Type Article
Acceptance Date Oct 31, 2022
Online Publication Date Nov 10, 2022
Publication Date Nov 10, 2022
Deposit Date Dec 7, 2022
Publicly Available Date Dec 7, 2022
Journal Frontiers in Oncology
Publisher Frontiers Media
Volume 12
DOI https://doi.org/10.3389/fonc.2022.1081171
Publisher URL https://doi.org/10.3389/fonc.2022.1081171

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