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Total esophagogastric and cologastric dissociation in neurologically normal children: systematic review.

Negri, E; Coletta, R; Bici, K; Bianchi, A; Morabito, A

Total esophagogastric and cologastric dissociation in neurologically normal children: systematic review. Thumbnail


Authors

E Negri

R Coletta

K Bici

A Bianchi

A Morabito



Abstract

Total esophagogastric dissociation (TEGD) was first described by Bianchi as a definitive procedure for gastroesophageal reflux disease (GERD) in neurologically impaired children. In the last 20 years, different centers extended the indication to neurologically normal (NN) patients with GERD associated with congenital or acquired esophageal anomalies. The aim of this paper is to analyze the role of TEGD in this cluster of patients. A PubMed and Google Scholar search was conducted. All cases of NN children who underwent TEGD for GERD were collected. Patient characteristics and outcomes were analyzed. Complications were classified according to Clavien-Dindo classification. Forty-eight children were identified. In 56.25%, TEGD was the first anti-reflux procedure, while in 43.75% it was performed after failed fundoplications. Mean follow-up was 5.5 years. Mortality related to surgery was 2.08%. All of the survivors improved their condition, with resolution of GERD and weight gain. In addition, 50% of children weaned off enteral nutrition, with 14.6% having their gastrostomy removed, while 41.67% maintained partial enteral supplementation. Respiratory symptoms almost disappeared in 54.17% of patients. This review suggests that TEGD can also be considered for NN children where conventional methods seem insufficient to control reflux and preserve pulmonary function. Nevertheless, long-term follow-up is still required.

Citation

Negri, E., Coletta, R., Bici, K., Bianchi, A., & Morabito, A. (2022). Total esophagogastric and cologastric dissociation in neurologically normal children: systematic review. Children, 9(7), 999. https://doi.org/10.3390/children9070999

Journal Article Type Article
Acceptance Date Jun 28, 2022
Online Publication Date Jul 2, 2022
Publication Date Jul 2, 2022
Deposit Date Sep 2, 2022
Publicly Available Date Sep 2, 2022
Journal Children
Publisher MDPI
Volume 9
Issue 7
Pages 999
DOI https://doi.org/10.3390/children9070999
Publisher URL https://doi.org/10.3390/children9070999

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