C Beadsmoore
Healthy passive cigarette smokers have increased pulmonary alveolar permeability
Beadsmoore, C; Cheow, HK; Szczepura, K; Ruparelia, P; Michael Peters, A
Authors
HK Cheow
Ms Katy Szczepura K.Szczepura@salford.ac.uk
Associate Professor/Reader
P Ruparelia
A Michael Peters
Abstract
Question
Does passive smoking have a measurable effect on lung function in otherwise healthy subjects? There is current interest concerning passive smoking but no objective evidence showing that it has any impact on lung function.
Methods
The pulmonary clearance rate of 99mTc-DTPA was measured in 21 healthy volunteers after inhalation as a radio-aerosol and compared between healthy cigarette smokers, passive smokers and non-smokers. All volunteers had normal lung function.
Results
Clearance half-times in healthy passive smokers (n=5) were longer than in healthy smokers (n=6) but clearly shorter compared with healthy non-smokers (n=10) with respective mean values of 45.2 (SD 8.3), 24.3 (8.6) and 80.3 (20) min.
Conclusion
Passive smoking has a functional impact on the lung blood/gas barrier.
Citation
Beadsmoore, C., Cheow, H., Szczepura, K., Ruparelia, P., & Michael Peters, A. (2007). Healthy passive cigarette smokers have increased pulmonary alveolar permeability. Nuclear Medicine Communications, 28(2), 75-77. https://doi.org/10.1097/MNM.0b013e328013eb1e
Journal Article Type | Article |
---|---|
Acceptance Date | Oct 27, 2006 |
Publication Date | Feb 1, 2007 |
Deposit Date | Feb 26, 2021 |
Journal | Nuclear Medicine Communications |
Print ISSN | 0143-3636 |
Electronic ISSN | 1473-5628 |
Publisher | Lippincott, Williams & Wilkins |
Volume | 28 |
Issue | 2 |
Pages | 75-77 |
DOI | https://doi.org/10.1097/MNM.0b013e328013eb1e |
Publisher URL | https://doi.org/10.1097/MNM.0b013e328013eb1e |
Related Public URLs | http://www.nuclearmedicinecomm.com/ |
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