A comparative analysis of the effects of two augmenters on the sensitivity of vertebral biomechanical behavior in vertebroplasty

Yuewan, S; Dongmei, W; Jingchuan, S; Liu, A; Jiangang, S

Abstract

The treatment of osteoporotic vertebral compression fractures (OVCFS) by transvertebral bone graft and augmentation (TBGA) has achieved satisfactory clinical results, but its biomechanical effects are not clear. The purpose of this study was to investigate the biomechanical effects of TBGA and compare the biomechanical sensitivity of the augmenter used in TBGA — a cylindrical enhancement device (CED) with bone cement. The finite element (FE) model of healthy segments T11-L3 (M1) was built, and two other models with L1 augmentation (M2, M3) were established to simulate CED and bone cement treatment, respectively. The stress and displacement distribution of the three models under five physiological loads were calculated and analyzed by the FE method. Based on the results, the sensitivities of biomechanical parameters to the degree of osteoporosis (DO) and loads were analyzed by linear fitting method using dummy variables. With the increase of DO, the CED is superior to bone cement in preventing the fractures of the augmented vertebral and the adjacent vertebral under the set loading conditions. Simulating TBGA method, the model 2 with L1 reconstructed was closer to the normal T11-L3 model in terms of sensitivity of stress and displacement under different loading conditions.

Citation

Yuewan, S., Dongmei, W., Jingchuan, S., Liu, A., & Jiangang, S. (2020). A comparative analysis of the effects of two augmenters on the sensitivity of vertebral biomechanical behavior in vertebroplasty. Journal of Mechanics in Medicine and Biology, 20(04), 2050007. https://doi.org/10.1142/s0219519420500074

• Journal Article Type: Article
• Acceptance Date: Feb 13, 2020
• Online Publication Date: May 19, 2020
• Publication Date: May 19, 2020
• Deposit Date: Jun 5, 2020
• Journal: Journal of Mechanics in Medicine and Biology
• Print ISSN: 0219-5194
• Electronic ISSN: 1793-6810
• Publisher: World Scientific Publishing
• Volume: 20
• Issue: 04
• Pages: 2050007
• DOI: https://doi.org/10.1142/s0219519420500074
• Keywords: Biomedical Engineering
• Publisher URL: https://doi.org/10.1142/S0219519420500074
• Related Public URLs: http://www.worldscientific.com/worldscinet/jmmb
• Additional Information: Additional Information : ** From Crossref via Jisc Publications Router **Journal IDs: pissn 0219-5194; eissn 1793-6810 **History: published_online 19-05-2020