Priorities for nutrition research in pediatric critical care

Tume, LN; Valla, FV; Floh, A; Goday, P; Jotterand-Chapparo, C; Larsen, B; Lee, J; Moreno, Y; Pathan, N; Verbruggen, S; Mehta, N

Abstract

Background: Widespread variation exists in pediatric critical care nutrition practices, largely because of the scarcity of evidence
to guide best practice recommendations. Objective: The objective of this paper was to develop a list of topics to be prioritized for
nutrition research in pediatric critical care in the next 10 years. Methods: A modified 3-round Delphi process was undertaken by
a newly established multidisciplinary group comprising 11 international researchers in the field of pediatric critical care nutrition.
Items were ranked on a 5-point Likert scale. Results: Forty-five research topics (with a mean priority score >3(0-5) were identified
within the following 10 domains: the pathophysiology and impact of malnutrition in critical illness; nutrition assessment: nutrition
risk assessment and biomarkers; accurate assessment of energy requirements in all phases of critical illness; the role of protein
intake; the role of pharmaco-nutrition; effective and safe delivery of enteral nutrition; enteral feeding intolerance: assessment and
management; the role of parenteral nutrition; the impact of nutrition status and nutrition therapies on long-termpatient outcomes;
and nutrition therapies for specific populations. Ten top research topics (that received a mean score >4(0-5) were identified as the
highest priority for research. Conclusions: This paper has identified important consensus-derived priorities for clinical research
in pediatric critical care nutrition. Future studies should determine topics that are a priority for patients and parents. Research
funding should target these priority areas and promote an international collaborative approach to research in this field, with a
focus on improving relevant patient outcomes.

Citation

Tume, L., Valla, F., Floh, A., Goday, P., Jotterand-Chapparo, C., Larsen, B., …Mehta, N. (2019). Priorities for nutrition research in pediatric critical care. Journal of Parenteral and Enteral Nutrition, 43(7), 853-862. https://doi.org/10.1002/jpen.1498

• Journal Article Type: Article
• Acceptance Date: Dec 3, 2018
• Online Publication Date: Dec 26, 2018
• Publication Date: Sep 11, 2019
• Deposit Date: Sep 4, 2019
• Journal: Journal of Parenteral and Enteral Nutrition
• Print ISSN: 0148-6071
• Electronic ISSN: 1941-2444
• Publisher: SAGE Publications
• Volume: 43
• Issue: 7
• Pages: 853-862
• DOI: https://doi.org/10.1002/jpen.1498
• Publisher URL: https://doi.org/10.1002/jpen.1498
• Related Public URLs: https://onlinelibrary.wiley.com/journal/19412444
• Additional Information: Access Information : This is the peer reviewed version of the following article: Tume, L.N., Valla, F.V., Floh, A.A., Goday, P., Jotterand Chaparro, C., Larsen, B., Lee, J.H., Moreno, Y.M.F., Pathan, N., Verbruggen, S. and Mehta, N.M. (2019), Priorities for Nutrition Research in Pediatric Critical Care. Journal of Parenteral and Enteral Nutrition, 43: 853-862., which has been published in final form at https://doi.org/10.1002/jpen.1498. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions.