Muscle activation during gait in children with Duchenne muscular dystrophy

Ropars, J; Lempereur, M; Vuillerot, C; Tiffreau, V; Peudenier, S; Cuisset, J-M; Pereon, Y; Leboeuf, FY; Delporte, L; Delpierre, Y; Gross, R; Brochard, S

Abstract

The aim of this prospective study was to investigate changes in muscle activity during gait in children with Duchenne muscular Dystrophy (DMD). Dynamic surface electromyography recordings (EMGs) of 16 children with DMD and pathological gait were compared with those of 15 control children. The activity of the rectus femoris (RF), vastus lateralis (VL), medial hamstrings (HS), tibialis anterior (TA) and gastrocnemius soleus (GAS) muscles was recorded and analysed quantitatively and qualitatively. The overall muscle activity in the children with DMD was significantly different from that of the control group. Percentage activation amplitudes of RF, HS and TA were greater throughout the gait cycle in the children with DMD and the timing of GAS activity differed from the control children. Significantly greater muscle coactivation was found in the children with DMD. There were no significant differences between sides. Since the motor command is normal in DMD, the hyper-activity and co-contractions likely compensate for gait instability and muscle weakness, however may have negative consequences on the muscles and may increase the energy cost of gait. Simple rehabilitative strategies such as targeted physical therapies may improve stability and thus the pattern of muscle activity.

Citation

Ropars, J., Lempereur, M., Vuillerot, C., Tiffreau, V., Peudenier, S., Cuisset, J., …Brochard, S. (2016). Muscle activation during gait in children with Duchenne muscular dystrophy. PLoS ONE, 11(9), e0161938. https://doi.org/10.1371/journal.pone.0161938

• Journal Article Type: Article
• Acceptance Date: Aug 15, 2016
• Online Publication Date: Sep 13, 2016
• Publication Date: Sep 13, 2016
• Deposit Date: Oct 5, 2018
• Publicly Available Date: Oct 5, 2018
• Journal: PLoS ONE
• Publisher: Public Library of Science
• Volume: 11
• Issue: 9
• Pages: e0161938
• DOI: https://doi.org/10.1371/journal.pone.0161938
• Publisher URL: https://doi.org/10.1371/journal.pone.0161938
• Related Public URLs: https://journals.plos.org/plosone/