High-resolution sizing of monolayer-protected gold clusters by differential centrifugal sedimentation

Krpetic, Z; Davidson, AM; Volk, M; Lévy, R; Brust, M; Cooper, DL

Abstract

Differential centrifugal sedimentation (DCS) has been applied to accurately size ligand-protected gold hydrosols in the 10 to 50 nm range. A simple protocol is presented to correct for particle density variations due to the presence of the ligand shell, which is formed here by either polyethylene glycol-substituted alkane thiols (PEG-alkane thiols) of different chain length or oligopeptides. The method gives reliable data for all particle sizes investigated and lends itself to rapid routine sizing of nanoparticles. Unlike TEM, DCS is highly sensitive to small changes in the thickness of the organic ligand shell and can be applied to monitor shell thickness variations of as little as 0.1 nm on particles of a given core size.

Citation

Krpetic, Z., Davidson, A., Volk, M., Lévy, R., Brust, M., & Cooper, D. (2013). High-resolution sizing of monolayer-protected gold clusters by differential centrifugal sedimentation. ACS nano, 7(10), 8881-8890. https://doi.org/10.1021/nn403350v

• Journal Article Type: Article
• Online Publication Date: Sep 23, 2013
• Publication Date: Sep 23, 2013
• Deposit Date: Oct 6, 2016
• Journal: ACS Nano
• Print ISSN: 1936-0851
• Publisher: American Chemical Society
• Volume: 7
• Issue: 10
• Pages: 8881-8890
• DOI: https://doi.org/10.1021/nn403350v
• Publisher URL: http://dx.doi.org/10.1021/nn403350v
• Related Public URLs: http://pubs.acs.org/doi/abs/10.1021/nn403350v
• Additional Information: Projects : FP7- NMP-2010-EU-MEXICO;CONACYT