Current status of Clonorchis sinensis and clonorchiasis in China

Lai, D; Hong, X; Su, B; Liang, C; Hide, G; Zhang, X; Yu, X; Lun, Z

Abstract

The oriental liver fluke, Clonorchis sinensis, a pathogen causing clonorchiasis, is of major socio-economic importance
in East Asia, including China, Korea and Vietnam. This parasite is nowrecognized as a biocarcinogen strongly
linked to cholangiocarcinoma in humans. Here,we describe the status of clonorchiasis in China, where it has been
estimated that more than 15 million patients are affected. This paper also summarizes the major advances in the
field of clonorchiasis research during last decade, including diagnosis techniques, pathogenesis and genome/
transcriptome/proteome studies in the last years.We strongly hope that our work can stimulate the governments
of the countries or regions where clonorchiasis is endemic to pay more attention to this disease and establish
related guidelines to prevent and control it.

Citation

Lai, D., Hong, X., Su, B., Liang, C., Hide, G., Zhang, X., …Lun, Z. (2016). Current status of Clonorchis sinensis and clonorchiasis in China. Transactions of The Royal Society of Tropical Medicine and Hygiene, 110(1), 21-27. https://doi.org/10.1093/trstmh/trv100

• Journal Article Type: Article
• Acceptance Date: Oct 21, 2015
• Publication Date: Jan 6, 2016
• Deposit Date: Jan 11, 2016
• Publicly Available Date: Jan 1, 2017
• Journal: Transactions of the Royal Society of Tropical Medicine & Hygiene
• Print ISSN: 0035-9203
• Electronic ISSN: 1878-3503
• Publisher: Oxford University Press
• Volume: 110
• Issue: 1
• Pages: 21-27
• DOI: https://doi.org/10.1093/trstmh/trv100
• Publisher URL: http://trstmh.oxfordjournals.org/content/110/1/21.full?sid=4b63ef03-1c18-4e66-8382-f37e173ba646
• Related Public URLs: http://www.salford.ac.uk/environment-life-sciences/els-academics/geoff-hide; http://trstmh.oxfordjournals.org/
• Additional Information: Funders : Guangzhou Science Technology and Innovation Commission;Natural Sciences Foundation of Guangdong Province; Projects : Current status of Clonorchis sinensis and clonorchiasis in China; Grant Number: 201506010011; Grant Number: 2014A030313164