Mapping neurobiological alterations in obsessive-compulsive disorder

Allely, CS

Abstract

This article will explore recent studies that have identified alterations in brain regions in individuals with obsessive–compulsive disorder (OCD). Specifically, alterations have been found in the cortical surface anatomy, the white matter, the gray matter, the cerebellum, the olfactory-processing structures, the temporal lobe, the prefrontal cortex, and the amygdala. Although some emerging data implicate these brain regions in OCD, the cortico–striatal–thalamic–cortical circuitry remains the prime focus of research. This article will also give an overview of studies that have found different symptom dimensions in individuals with OCD to have distinct neural correlates.

Citation

Allely, C. Mapping neurobiological alterations in obsessive-compulsive disorder. In Brain Mapping (993-1000). Elsevier. https://doi.org/10.1016/B978-0-12-397025-1.00124-X

• Deposit Date: Apr 2, 2015
• Publisher: Elsevier
• Pages: 993-1000
• Book Title: Brain Mapping
• DOI: https://doi.org/10.1016/B978-0-12-397025-1.00124-X
• Publisher URL: http://dx.doi.org/10.1016/B978-0-12-397025-1.00124-X
• Related Public URLs: http://www.sciencedirect.com/science/article/pii/B978012397025100124X