Species interactions in a parasite community drive infection risk in a wildlife population

Telfer, S; Lambin, X; Birtles, RJ; Beldomenico, P; Burthe, S; Paterson, S; Begon, M

Abstract

Most hosts, including humans, are simultaneously or sequentially infected with several parasites.
A key question is whether patterns of coinfection arise because infection by one parasite species
affects susceptibility to others or because of inherent differences between hosts. We used time-series
data from individual hosts in natural populations to analyze patterns of infection risk for a
microparasite community, detecting large positive and negative effects of other infections. Patterns
remain once variations in host susceptibility and exposure are accounted for. Indeed, effects are
typically of greater magnitude, and explain more variation in infection risk, than the effects
associated with host and environmental factors more commonly considered in disease studies. We
highlight the danger of mistaken inference when considering parasite species in isolation rather
than parasite communities.

Citation

Telfer, S., Lambin, X., Birtles, R., Beldomenico, P., Burthe, S., Paterson, S., & Begon, M. (2010). Species interactions in a parasite community drive infection risk in a wildlife population. Science, 330(6001), 243-246. https://doi.org/10.1126/science.1190333

• Journal Article Type: Article
• Publication Date: Jan 1, 2010
• Deposit Date: Dec 20, 2011
• Journal: Science
• Print ISSN: 0036-8075
• Publisher: American Association for the Advancement of Science
• Peer Reviewed: Peer Reviewed
• Volume: 330
• Issue: 6001
• Pages: 243-246
• DOI: https://doi.org/10.1126/science.1190333
• Publisher URL: http://dx.doi.org/10.1126/science.1190333