Stroke-related differences in axial body segment coordination during preplanned and reactive changes in walking direction

Hollands, K; van Vliet, P; Zietz, D; Wing, AM; Hollands, MA

Abstract

This study quantitatively describes differences
between participants with hemiparetic stroke and agematched
healthy participants in axial body segment and gait
kinematics during a direction change task. Participants were
required to change walking direction by 45�, either to their
left or right, at the midpoint of a 6-m path. Participants were
visually cued either at the start of the walk (pre-planned) or
one stride before they reached the turn point (reactive). The
sequence and inter-segmental timing of axial orientation
onset was preserved in participants with stroke. Analysis of
a subgroup of stroke survivors indicated that participants
with lesions affecting the basal ganglia (BG) took significantly
longer time than control participants to initiate the
reorientation synergy when making turns to their nonparetic
side. We hypothesize that these differences are a
product of asymmetrical activity of dopaminergic pathways
in the brain resulting from compromised BG function.

Citation

Hollands, K., van Vliet, P., Zietz, D., Wing, A., & Hollands, M. (2010). Stroke-related differences in axial body segment coordination during preplanned and reactive changes in walking direction. Experimental Brain Research, 202(3), 591-604. https://doi.org/10.1007/s00221-010-2162-1

• Journal Article Type: Article
• Publication Date: May 1, 2010
• Deposit Date: Dec 21, 2010
• Journal: Experimental Brain Research
• Print ISSN: 0014-4819
• Publisher: Springer Verlag
• Peer Reviewed: Peer Reviewed
• Volume: 202
• Issue: 3
• Pages: 591-604
• DOI: https://doi.org/10.1007/s00221-010-2162-1
• Publisher URL: http://dx.doi.org/10.1007/s00221-010-2162-1