All Outputs (3)

Human brain shows recurrent non-canonical microRNA editing events enriched for seed sequence with possible functional consequence (2020)
Journal Article
Paul, D., Ansari, A., Lal, M., & Mukhopadhyay, A. (2020). Human brain shows recurrent non-canonical microRNA editing events enriched for seed sequence with possible functional consequence. Non-Coding RNA, 6(2), e21. https://doi.org/10.3390/ncrna6020021

RNA editing is a post-transcriptional modification, which can provide tissue-specific functions not encoded in DNA. Adenosine-to-inosine is the predominant editing event and, along with cytosine-to-uracil changes, constitutes canonical editing. The r... Read More about Human brain shows recurrent non-canonical microRNA editing events enriched for seed sequence with possible functional consequence.

Genetic landscape of autism spectrum disorder in Vietnamese children (2020)
Journal Article
Tran, K., Le, V., Bui, H., Do, D., Ly, H., Nguyen, H., …Nguyen, L. (2020). Genetic landscape of autism spectrum disorder in Vietnamese children. Scientific reports, 10(1), 5034. https://doi.org/10.1038/s41598-020-61695-8

Autism spectrum disorder (ASD) is a complex disorder with an unclear aetiology and an estimated global prevalence of 1%. However, studies of ASD in the Vietnamese population are limited. Here, we first conducted whole exome sequencing (WES) of 100 ch... Read More about Genetic landscape of autism spectrum disorder in Vietnamese children.

Fusion transcripts in normal human cortex increase with age and show distinct genomic features for single cells and tissues (2020)
Journal Article
Mehani, B., Narta, K., Paul, D., Raj, A., Kumar, D., Sharma, A., …Mukhopadhyay, A. (2020). Fusion transcripts in normal human cortex increase with age and show distinct genomic features for single cells and tissues. Scientific reports, 10(1), 1368. https://doi.org/10.1038/s41598-020-58165-6

Fusion transcripts can contribute to diversity of molecular networks in the human cortex. In this study, we explored the occurrence of fusion transcripts in normal human cortex along with single neurons and astrocytes. We identified 1305 non-redundan... Read More about Fusion transcripts in normal human cortex increase with age and show distinct genomic features for single cells and tissues.