The activities of suaveolol and other compounds from Hyptis suaveolens and Momordica charantia against the aetiological agents of African trypanosomiasis, leishmaniasis and malaria

Oaikhena, Enimie E.; Yahaya, Umar A.; Abdulsalami, Sani M.; Egbe, Nkechi L.; Adeyemi, Modupe M.; Ungogo, Marzuq A.; Ebiloma, Godwin U.; Zoiku, Felix K.; Fordjour, Prince A.; Elati, Hamza A.A.; Quashie, Neils B.; Igoli, John O.; Gray, Alexander I.; Lawson, Christopher; Ferro, Valerie A.; de Koning, Harry P.

doi:10.1016/j.exppara.2024.108807

All Outputs (2)

Nanostructured Lipid Carrier for Intracellular Delivery of a Bis(pyridine-2-carboxamidine) DNA Minor Groove Binder Active against Leishmania (2025)
Journal Article

Two types of nanostructured lipid carrier (NLC) formulations of the antileishmanial DNA minor groove binding compound 4-(picolinimidamido)-N-(4-(picolinimidamido)phenyl)benzamide (1) were synthesized by the microemulsion method to evaluate their pote... Read More about Nanostructured Lipid Carrier for Intracellular Delivery of a Bis(pyridine-2-carboxamidine) DNA Minor Groove Binder Active against Leishmania.

The activities of suaveolol and other compounds from Hyptis suaveolens and Momordica charantia against the aetiological agents of African trypanosomiasis, leishmaniasis and malaria (2024)
Journal Article

African trypanosomiasis and malaria are among the most severe health challenges to humans and livestock in Africa and new drugs are needed. Leaves of Hyptis suaveolens Kuntze (Lamiaceae) and Momordica charantia L. (Cucurbitaceae) were extracted with... Read More about The activities of suaveolol and other compounds from Hyptis suaveolens and Momordica charantia against the aetiological agents of African trypanosomiasis, leishmaniasis and malaria.