All Outputs (3)

Assessment of an ex vivo porcine lung model to investigate host-microbe interactions in cases of ventilator associated pneumonia (2021)
Thesis
Barber, E. (in press). Assessment of an ex vivo porcine lung model to investigate host-microbe interactions in cases of ventilator associated pneumonia. (Dissertation). University of Salford

VAP is described as a pneumonic lung infection afflicting those that have been mechanically ventilated typically with an endotracheal tube. Unfortunately, there is no singular diagnostic test for VAP (Grossman & Fein, 2000) or ‘gold standard’ for the... Read More about Assessment of an ex vivo porcine lung model to investigate host-microbe interactions in cases of ventilator associated pneumonia.

Proinflammatory cytokines as mediators of phenotypic change in bacteria implicated in ventilator-associated pneumonia (2021)
Thesis
Tompsett, A. Proinflammatory cytokines as mediators of phenotypic change in bacteria implicated in ventilator-associated pneumonia. (Thesis). University of Salford

Ventilator-associated pneumonia (VAP) is a common hospital-acquired infection in intensive care. VAP is associated with increased hospital stay, healthcare costs, and high mortality. VAP is difficult to diagnose and manage appropriately, leading to w... Read More about Proinflammatory cytokines as mediators of phenotypic change in bacteria implicated in ventilator-associated pneumonia.

Do bacteria implicated in Ventilator-Associated Pneumonia adapt to antibiotic exposure? (2020)
Thesis
Parkes, J. Do bacteria implicated in Ventilator-Associated Pneumonia adapt to antibiotic exposure?. (Dissertation). University of Salford

Antibiotics have been key to the treatment of bacterial infections since their introduction, but the increasing levels of antimicrobial resistance is a concern. Patients with serious respiratory conditions, such as those often encountered within crit... Read More about Do bacteria implicated in Ventilator-Associated Pneumonia adapt to antibiotic exposure?.