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Biochemical changes and cytotoxicity associated with methionine depletion in paediatric central nervous system tumour cell lines (2009)
Journal Article
Najim, N., Podmore, I., Mcgown, A., & Estlin, E. (2009). Biochemical changes and cytotoxicity associated with methionine depletion in paediatric central nervous system tumour cell lines. Anticancer Research, 29(8), 2971-2976

The aim of this study was to investigate the importance of the extent and duration of methionine depletion as a cause of cytotoxicity for CNS tumour cell lines, and also to investigate the associated in vitro cellular biochemical responses. MATERIALS... Read More about Biochemical changes and cytotoxicity associated with methionine depletion in paediatric central nervous system tumour cell lines.

Methionine restriction reduces the chemosensitivity of central nervous system tumour cell lines (2009)
Journal Article
Najim, N., Podmore, I., Mcgown, A., & Estlin, E. (2009). Methionine restriction reduces the chemosensitivity of central nervous system tumour cell lines. Anticancer Research, 29(8), 3101-3108

The aim of this study was to investigate the effects of methionine depletion with cytotoxic agents that are potentially influenced by depletion of methionine, and are known to have a role in CNS tumour treatments for children. MATERIALS AND METHODS:... Read More about Methionine restriction reduces the chemosensitivity of central nervous system tumour cell lines.