All Outputs (5)

The effect of normal human serum on the mouse trypanosome Trypanosoma musculi in vitro and in vivo (2017)
Journal Article
Zhang, X., Hong, X., Li, S., Lai, D., Hide, G., Lun, Z., & Wen, Y. (2018). The effect of normal human serum on the mouse trypanosome Trypanosoma musculi in vitro and in vivo. Experimental Parasitology, 184, 115-120. https://doi.org/10.1016/j.exppara.2017.12.005

Trypanosoma musculi, a common blood flagellate found in mice, is similar in morphology and life cycle to the rat trypanosome T. lewisi. Both species belong to the subgenus Herpetosoma, and as T. lewisi has recently been shown to be a zoonotic pathoge... Read More about The effect of normal human serum on the mouse trypanosome Trypanosoma musculi in vitro and in vivo.

Nitric oxide blocks the development of the human parasite Schistosoma japonicum (2017)
Journal Article
Shen, J., Lai, D., Wilson, R., Chen, Y., Wang, L., Yu, Z., …Lun, Z. (2017). Nitric oxide blocks the development of the human parasite Schistosoma japonicum. Proceedings of the National Academy of Sciences of the United States of America, 114(38), 10214-10219. https://doi.org/10.1073/pnas.1708578114

Human schistosomiasis, caused by Schistosoma species, is a major public health problem affecting more than 700 million people in 78 countries, with over 40 mammalian host reservoir species complicating the transmission ecosystem. The primary cause of... Read More about Nitric oxide blocks the development of the human parasite Schistosoma japonicum.

Genetic analyses of Chinese isolates of Toxoplasma gondii reveal a new genotype with high virulence to murine hosts (2017)
Journal Article
Gao, J., Xie, Y., Xu, Z., Chen, H., Hide, G., Yang, T., …Lun, Z. (2017). Genetic analyses of Chinese isolates of Toxoplasma gondii reveal a new genotype with high virulence to murine hosts. Veterinary Parasitology, 241, 52-60. https://doi.org/10.1016/j.vetpar.2017.05.007

A great deal of evidence demonstrates that a strongly clonal population structure of Toxoplasma gondii strains exists in humans and animals in North America and Europe, while the strains from South America are genetically separate and more diverse. P... Read More about Genetic analyses of Chinese isolates of Toxoplasma gondii reveal a new genotype with high virulence to murine hosts.

Recombinant α-actinin subunit antigens of Trichomonas vaginalis as potential vaccine candidates in protecting against trichomoniasis (2017)
Journal Article
Xie, Y., Gao, J., Wu, Y., Tang, P., Hide, G., Lai, D., & Lun, Z. (2017). Recombinant α-actinin subunit antigens of Trichomonas vaginalis as potential vaccine candidates in protecting against trichomoniasis. Parasites and Vectors, 10(1), 83. https://doi.org/10.1186/s13071-017-2009-8

BACKGROUND: Human trichomoniasis caused by Trichomonas vaginalis is one of the most common sexually transmitted diseases with more than 200 million cases worldwide. It has caused a series of health problems to patients. For prevention and control of... Read More about Recombinant α-actinin subunit antigens of Trichomonas vaginalis as potential vaccine candidates in protecting against trichomoniasis.

Guanylate-binding Protein 1 (GBP1) contributes to the immunity of human mesenchymal stromal cells against toxoplasma gondii (2017)
Journal Article
Qin, A., Lai, D., Liu, Q., Huang, W., Wu, Y., Chen, X., …Xiang, A. (2017). Guanylate-binding Protein 1 (GBP1) contributes to the immunity of human mesenchymal stromal cells against toxoplasma gondii. Proceedings of the National Academy of Sciences, 114(6), 1365-1370. https://doi.org/10.1073/pnas.1619665114

Mesenchymal stromal cells (MSCs) have recently been shown to play important roles in mammalian host defenses against intracellular pathogens, but the molecular mechanism still needs to be clarified. We confirmed that human MSCs (hMSCs) pre-stimulated... Read More about Guanylate-binding Protein 1 (GBP1) contributes to the immunity of human mesenchymal stromal cells against toxoplasma gondii.