Acid microenvironment promotes cell survival of human bone sarcoma through the activation of cIAP proteins and NF-κB pathway
(2019)
Journal Article
Avnet, S., Chano, T., Massa, A., Bonuccelli, G., Lemma, S., Falzetti, L., …Baldini, N. (2019). Acid microenvironment promotes cell survival of human bone sarcoma through the activation of cIAP proteins and NF-κB pathway. American Journal of Cancer Research, 9(6), 1127-1144
Extracellular acidification is a very common cause of stress in tumor microenvironment and of Darwinian pressure. In acid areas of the tumor, most cancer cells are-albeit slowly proliferating-more resistant to cell death than those in well-perfused r... Read More about Acid microenvironment promotes cell survival of human bone sarcoma through the activation of cIAP proteins and NF-κB pathway.