All Outputs (5)

Long-term trends in helminth infections of wood mice (Apodemus sylvaticus) from the vicinity of Malham Tarn in North Yorkshire, England (2020)
Journal Article
Behnke, J., Rogan, M., Craig, P., Jackson, J., & Hide, G. (2021). Long-term trends in helminth infections of wood mice (Apodemus sylvaticus) from the vicinity of Malham Tarn in North Yorkshire, England. Parasitology, 184(4), 451-463. https://doi.org/10.1017/S0031182020002243

Helminth infections in wood mice (n=483), trapped over a period of 26 years in the woods surrounding Malham Tarn in N. Yorkshire, were analysed. Although ten species of helminths were identified, the overall mean species richness was 1.01 species/m... Read More about Long-term trends in helminth infections of wood mice (Apodemus sylvaticus) from the vicinity of Malham Tarn in North Yorkshire, England.

Novel organization of mitochondrial minicircles and guide RNAs in the zoonotic pathogen Trypanosoma lewisi (2020)
Journal Article
Li, S., Zhang, X., Lukeš, J., Li, B., Wang, J., Qu, L., …Lun, Z. (2020). Novel organization of mitochondrial minicircles and guide RNAs in the zoonotic pathogen Trypanosoma lewisi. Nucleic Acids Research, 48(17), 9747-9761. https://doi.org/10.1093/nar/gkaa700

Abstract Kinetoplastid flagellates are known for several unusual features, one of which is their complex mitochondrial genome, known as kinetoplast (k) DNA, composed of mutually catenated maxi- and minicircles. Trypanosoma lewisi is a member of the S... Read More about Novel organization of mitochondrial minicircles and guide RNAs in the zoonotic pathogen Trypanosoma lewisi.

Temperature is a key factor influencing the invasion and proliferation of Toxoplasma gondii in fish cells (2020)
Journal Article
Yang, Y., Yu, S., Chen, K., Hide, G., Lun, Z., & Lai, D. (2020). Temperature is a key factor influencing the invasion and proliferation of Toxoplasma gondii in fish cells. Experimental Parasitology, 217, 107966. https://doi.org/10.1016/j.exppara.2020.107966

Toxoplasma gondii has long been considered a ubiquitous parasite possessing the capacity of infecting virtually all warm-blooded animals globally. Occasionally, this parasite can also infect cold-blooded animals such as fish if their body temperature... Read More about Temperature is a key factor influencing the invasion and proliferation of Toxoplasma gondii in fish cells.

Human African trypanosomiasis : the current situation in endemic regions and the risks for non-endemic regions from imported cases (2020)
Journal Article
Gao, J., Qian, Z., Hide, G., Lai, D., Lun, Z., & Wu, Z. (2020). Human African trypanosomiasis : the current situation in endemic regions and the risks for non-endemic regions from imported cases. Parasitology, 147(9), 922-931. https://doi.org/10.1017/S0031182020000645

Human African trypanosomiasis (HAT) is caused by Trypanosoma brucei gambiense and T. b. rhodesiense and caused devastating epidemics during the 20th century. Due to effective control programs implemented in the last two decades, the number of repo... Read More about Human African trypanosomiasis : the current situation in endemic regions and the risks for non-endemic regions from imported cases.

Vacuolar ATPase depletion contributes to dysregulation of endocytosis in bloodstream forms of Trypanosoma brucei (2020)
Journal Article
Xu, Z., Li, F., Hide, G., Lun, Z., & Lai, D. (2020). Vacuolar ATPase depletion contributes to dysregulation of endocytosis in bloodstream forms of Trypanosoma brucei. Parasites and Vectors, 13(1), 214. https://doi.org/10.1186/s13071-020-04068-4

BACKGROUND Vacuolar H-ATPase (V-ATPase) is a highly conserved protein complex which hydrolyzes ATP and pumps protons to acidify vacuolar vesicles. Beyond its role in pH maintenance, the involvement of V-ATPase in endocytosis is well documented in... Read More about Vacuolar ATPase depletion contributes to dysregulation of endocytosis in bloodstream forms of Trypanosoma brucei.