Synthesis and evaluation of novel kinase inhibitors as anti-cancer agents
(2012)
Thesis
Kemp, T. Synthesis and evaluation of novel kinase inhibitors as anti-cancer agents. (Thesis). University of Salford
Disruption of protein kinase signalling pathways is often associated with cancer. The RhoA/ROCK kinase pathway has been shown to be constitutively expressed in many cancers and has also been shown to be involved in metastasis and apoptosis. ROCK is... Read More about Synthesis and evaluation of novel kinase inhibitors as anti-cancer agents.