All Outputs (2)

The role of interleukin-10 in coronary artery disease (2023)
Thesis
Samphire-Noden, B. (2023). The role of interleukin-10 in coronary artery disease. (Thesis). University of Salford

Coronary artery disease (CAD) is a leading cause of mortality and morbidity worldwide, accounting for 66,000 deaths annually in the UK. Atherosclerosis is the underlying pathophysiological mechanism which drives CAD progression, producing an inflamma... Read More about The role of interleukin-10 in coronary artery disease.

The effects of anthracyclines on calcium handling and contractility in sheep ventricular myocytes; role of oxidative stress (2023)
Thesis
Foster, A. (2023). The effects of anthracyclines on calcium handling and contractility in sheep ventricular myocytes; role of oxidative stress. (Thesis). University of Salford

Anthracyclines such as doxorubicin (DOX) and daunorubicin (DAUN) are effective chemotherapeutics and contribute to improved cancer survival rates in children and adults. However, anthracyclines exhibit acute and chronic cardiotoxicity which can produ... Read More about The effects of anthracyclines on calcium handling and contractility in sheep ventricular myocytes; role of oxidative stress.