All Outputs (5)

The role of interleukin-10 in coronary artery disease (2023)
Thesis
Samphire-Noden, B. (2023). The role of interleukin-10 in coronary artery disease. (Thesis). University of Salford

Coronary artery disease (CAD) is a leading cause of mortality and morbidity worldwide, accounting for 66,000 deaths annually in the UK. Atherosclerosis is the underlying pathophysiological mechanism which drives CAD progression, producing an inflamma... Read More about The role of interleukin-10 in coronary artery disease.

The effects of anthracyclines on calcium handling and contractility in sheep ventricular myocytes; role of oxidative stress (2023)
Thesis
Foster, A. (2023). The effects of anthracyclines on calcium handling and contractility in sheep ventricular myocytes; role of oxidative stress. (Thesis). University of Salford

Anthracyclines such as doxorubicin (DOX) and daunorubicin (DAUN) are effective chemotherapeutics and contribute to improved cancer survival rates in children and adults. However, anthracyclines exhibit acute and chronic cardiotoxicity which can produ... Read More about The effects of anthracyclines on calcium handling and contractility in sheep ventricular myocytes; role of oxidative stress.

Characterisation of inflammatory mediators in ischaemic heart disease (2022)
Thesis
Borun, A. Characterisation of inflammatory mediators in ischaemic heart disease. (Dissertation). University of Salford

Coronary artery disease (CAD) is one of the most common causes of death in general population. In the UK it accounts for 64000 deaths annually and there are currently 2.3 million people living with CAD. Persistent inflammation of myocardium is believ... Read More about Characterisation of inflammatory mediators in ischaemic heart disease.

The role of serum biomarkers and oxidative stress in Ischemic Heart Disease (2022)
Thesis
Riley, C. The role of serum biomarkers and oxidative stress in Ischemic Heart Disease. (Dissertation). University of Salford

Ischemic heart disease also referred to as coronary artery disease (CAD) is a leading cause of death worldwide. The primary pathological mechanism underlying CAD is atherosclerosis, an inflammatory process associated with an accumulation of lipids an... Read More about The role of serum biomarkers and oxidative stress in Ischemic Heart Disease.

The chemotherapeutic potential of Boswellia carterii oleoresins (2021)
Thesis
Jones, M. The chemotherapeutic potential of Boswellia carterii oleoresins. (Thesis). University of Salford

Cancer is a leading cause of death worldwide. Though effective treatments are available and reduce mortality, issues such as debilitating side-effects and drug resistance necessitate a need to develop alternatives. Natural products are a key and dive... Read More about The chemotherapeutic potential of Boswellia carterii oleoresins.