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All Outputs (5)

Alterations in Autophagy Marker Distribution in Different Genetic Subtypes of Frontotemporal Lobar Degeneration (2023)
Thesis
Heale, R. (2023). Alterations in Autophagy Marker Distribution in Different Genetic Subtypes of Frontotemporal Lobar Degeneration. (Thesis). University of Salford

Frontotemporal dementia (FTD) is the second most common type of early-onset dementia and is characterised by impairments in language and behavioural changes whilst memory is normally well preserved; it can be clinically subdivided into behavioural va... Read More about Alterations in Autophagy Marker Distribution in Different Genetic Subtypes of Frontotemporal Lobar Degeneration.

Exploring the influence of adipokines on neuronal function in Alzheimer’s disease (2021)
Thesis
Tomar, N. Exploring the influence of adipokines on neuronal function in Alzheimer’s disease. (Thesis). University of Salford

Alzheimer’s disease (AD) is one of the major causes of dementia. Alzheimer’s disease is an irreversible, slow neurodegenerative disease leading to memory and language impairment and amyloid-β plaques and intraneuronal neurofibrillary tangles are the... Read More about Exploring the influence of adipokines on neuronal function in Alzheimer’s disease.

Investigation into Toxoplasma gondii infection in relation to expression of neurodegenerative disease markers in natural mice populations (2020)
Thesis
Alshammari, A. (2020). Investigation into Toxoplasma gondii infection in relation to expression of neurodegenerative disease markers in natural mice populations. (Thesis). University of Salford

Toxoplasma gondii is a highly prevalent opportunistic protozoan parasite that has a remarkable capacity to infect humans and a range of warm-blooded animals. This research had two broad aims. Firstly, to investigating whether detection of T. gondii i... Read More about Investigation into Toxoplasma gondii infection in relation to expression of neurodegenerative disease markers in natural mice populations.

Investigating alterations in autophagy in Alzheimer’s disease using human brain tissue and skin-derived fibroblasts
Thesis
Stan, D. (in press). Investigating alterations in autophagy in Alzheimer’s disease using human brain tissue and skin-derived fibroblasts. (Thesis). University of Salford

Alzheimer’s disease (AD) is the main cause of dementia, affecting 500,000 people in the UK. Pathology of AD is characterised by the accumulation of abnormally phosphorylated tau protein within neurofibrillary tangles and plaques containing amyloid-β... Read More about Investigating alterations in autophagy in Alzheimer’s disease using human brain tissue and skin-derived fibroblasts.