Novel monoclonal antibody recognition of oxidative DNA damage adduct, deoxycytidine-glyoxal
(2003)
Journal Article
Mistry, N., Podmore, I., Cooke, M., Butler, P., Griffiths, H., Herbert, K., & Lunec, J. (2003). Novel monoclonal antibody recognition of oxidative DNA damage adduct, deoxycytidine-glyoxal. Laboratory Investigation, 83(2), 241-250. https://doi.org/10.1097/01.LAB0000053915.88556.ED
Glyoxal, a reactive aldehyde, is a decomposition product of lipid hydroperoxides, oxidative deoxyribose breakdown, or autoxidation of sugars, such as glucose. It readily forms DNA adducts, generating potential carcinogens such as glyoxalated deoxycyt... Read More about Novel monoclonal antibody recognition of oxidative DNA damage adduct, deoxycytidine-glyoxal.