All Outputs (3)

Temperate phages both mediate and drive adaptive evolution in pathogen biofilms (2016)
Journal Article
Davies, E., James, C., Williams, D., O'Brien, S., Fothergill, J., Haldenby, S., …Brockhurst, M. (2016). Temperate phages both mediate and drive adaptive evolution in pathogen biofilms. Proceedings of the National Academy of Sciences, 113(29), 8266-8271. https://doi.org/10.1073/pnas.1520056113

Temperate phages drive genomic diversification in bacterial pathogens. Phage-derived sequences are more common in pathogenic than non-pathogenic taxa, and are associated with changes in pathogen virulence. High abundance and mobilisation of temper... Read More about Temperate phages both mediate and drive adaptive evolution in pathogen biofilms.

Temperate phages enhance pathogen fitness in chronic lung infection (2016)
Journal Article
Davies, E. V., James, C. E., Kukavica-Ibrulj, I., Levesque, R. C., Brockhurst, M. A., & Winstanley, C. (2016). Temperate phages enhance pathogen fitness in chronic lung infection. ISME Journal, 10(10), 2553-2555. https://doi.org/10.1038/ismej.2016.51

The Liverpool Epidemic Strain (LES) is a polylysogenic, transmissible strain of Pseudomonas aeruginosa, capable of superinfecting existing P. aeruginosa respiratory infections in individuals with cystic fibrosis (CF). The LES phages are highly active... Read More about Temperate phages enhance pathogen fitness in chronic lung infection.

The role of temperate bacteriophages in bacterial infection (2016)
Journal Article
Davies, E., Winstanley, C., Fothergill, J., & James, C. (2016). The role of temperate bacteriophages in bacterial infection. FEMS Microbiology Letters, 363(5), fnw015. https://doi.org/10.1093/femsle/fnw015

Bacteriophages are viruses that infect bacteria. There are an estimated 1031 phage on the planet, making them the most abundant form of life. We are rapidly approaching the centenary of their identification, and yet still have only a limited understa... Read More about The role of temperate bacteriophages in bacterial infection.