All Outputs (2)

A mitochondrial based oncology platform for targeting cancer stem cells (CSCs) : MITO-ONC-RX (2018)
Journal Article
Sotgia, F., Ozsvari, B., Fiorillo, M., De Francesco, E., Bonuccelli, G., & Lisanti, M. (2018). A mitochondrial based oncology platform for targeting cancer stem cells (CSCs) : MITO-ONC-RX. Cell Cycle, 17(17), 2091-2100. https://doi.org/10.1080/15384101.2018.1515551

Here, we wish to propose a new systematic approach to cancer therapy, based on the targeting of mitochondrial metabolism, especially in cancer stem cells (CSCs). In the future, we envision that anti-mitochondrial therapy would ultimately be practiced... Read More about A mitochondrial based oncology platform for targeting cancer stem cells (CSCs) : MITO-ONC-RX.

Matcha green tea (MGT) inhibits the propagation of cancer stem cells (CSCs), by targeting mitochondrial metabolism, glycolysis and multiple cell signalling pathways (2018)
Journal Article
Bonuccelli, G., Sotgia, F., & Lisanti, M. (2018). Matcha green tea (MGT) inhibits the propagation of cancer stem cells (CSCs), by targeting mitochondrial metabolism, glycolysis and multiple cell signalling pathways. Aging, 10(8), 1867-1883. https://doi.org/10.18632/aging.101483

Matcha green tea (MGT) is a natural product that is currently used as a dietary supplement and may have significant anti-cancer properties. However, the molecular mechanism(s) underpinning its potential health benefits remain largely unknown. Here, w... Read More about Matcha green tea (MGT) inhibits the propagation of cancer stem cells (CSCs), by targeting mitochondrial metabolism, glycolysis and multiple cell signalling pathways.