Silver nanoparticles impair retinoic acid-inducible gene I mediated mitochondrial anti-viral immunity by blocking the autophagic flux in lung epithelial cells

Villeret, B; Dieu, A; Straube, M; Solhonne, B; Miklavc, P; Hamadi, S; Le Borgne, R; Mailleux, A; Norel, X; Aerts, J; Diallo, D; Rouzet, F; Dietl, P; Sallenave, J-M; Garcia-Verdugo, I

doi:10.1021/acsnano.7b06934

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Silver nanoparticles impair retinoic acid-inducible gene I mediated mitochondrial anti-viral immunity by blocking the autophagic flux in lung epithelial cells (2018)
Journal Article
Villeret, B., Dieu, A., Straube, M., Solhonne, B., Miklavc, P., Hamadi, S., …Garcia-Verdugo, I. (2018). Silver nanoparticles impair retinoic acid-inducible gene I mediated mitochondrial anti-viral immunity by blocking the autophagic flux in lung epithelial cells. ACS nano, 12(2), 1188-1202. https://doi.org/10.1021/acsnano.7b06934

Silver nanoparticles (AgNPs) are microbicidal agents which could be potentially used as alternative to antivirals to treat human infectious diseases, especially Influenza virus infection where antivirals have generally proven unsuccessful. However, c... Read More about Silver nanoparticles impair retinoic acid-inducible gene I mediated mitochondrial anti-viral immunity by blocking the autophagic flux in lung epithelial cells.