All Outputs (2)

Novel copper-catalysed coupling reactions of diphenylmethane (2021)
Thesis
Breski, A. (in press). Novel copper-catalysed coupling reactions of diphenylmethane. (Dissertation). University of Salford

In this thesis, a novel synthesis of the drug fendiline was attempted. Fendiline was sold commercially as an angina therapeutic, and recent studies have shown that it is also anti-malarial and has activity against cancers with a high mortality rate.... Read More about Novel copper-catalysed coupling reactions of diphenylmethane.

Establishing a structure-activity-relationship for small molecule non-sugar glycomimetics (2021)
Thesis
Dobiecki-Davies, J. Establishing a structure-activity-relationship for small molecule non-sugar glycomimetics. (Dissertation). University of Salford

DAOY Medullablastoma cells are highly invasive, mobile and can cause severe neurological and physical illness in patients affected by this cancer. Previous work by Wilkinson & Co-workers (2017) showed that some small-molecule non-sugar glycomimetic d... Read More about Establishing a structure-activity-relationship for small molecule non-sugar glycomimetics.