All Outputs (2)

FoxO3a Drives the Metabolic Reprogramming in Tamoxifen-Resistant Breast Cancer Cells Restoring Tamoxifen Sensitivity (2023)
Journal Article
Fiorillo, M., Ricci, E., Fava, M., Longobucco, C., Sotgia, F., Rizza, P., …Sisci, D. (in press). FoxO3a Drives the Metabolic Reprogramming in Tamoxifen-Resistant Breast Cancer Cells Restoring Tamoxifen Sensitivity. Cells, 12(24), 2777. https://doi.org/10.3390/cells12242777

Tamoxifen-resistant breast cancer cells (TamR-BCCs) are characterized by an enhanced metabolic phenotype compared to tamoxifen-sensitive cells. FoxO3a is an important modulator of cell metabolism, and its deregulation has been involved in the acquisi... Read More about FoxO3a Drives the Metabolic Reprogramming in Tamoxifen-Resistant Breast Cancer Cells Restoring Tamoxifen Sensitivity.

Antibiotics that target mitochondria extend lifespan in C. elegans (2023)
Journal Article
Bonuccelli, G., Brooks, D. R., Shepherd, S., Sotgia, F., Lisanti, M. P., Brooks, D. R., & Lisanti, M. P. (in press). Antibiotics that target mitochondria extend lifespan in C. elegans. Aging, 15(21), 11764-11781. https://doi.org/10.18632/aging.205229

Aging is a continuous degenerative process caused by a progressive decline of cell and tissue functions in an organism. It is induced by the accumulation of damage that affects normal cellular processes, ultimately leading to cell death. It has been... Read More about Antibiotics that target mitochondria extend lifespan in C. elegans.