Prof Arijit Mukhopadhyay's Outputs (2)

Identification of miR-379/miR-656 (C14MC) cluster downregulation and associated epigenetic and transcription regulatory mechanism in oligodendrogliomas (2018)
Journal Article
Kumar, A., Nayak, S., Pathak, P., Purkait, S., Malgulawar, P., Sharma, M., …Sarkar, C. (2018). Identification of miR-379/miR-656 (C14MC) cluster downregulation and associated epigenetic and transcription regulatory mechanism in oligodendrogliomas. Journal of Neuro-Oncology, 139(1), 23-31. https://doi.org/10.1007/s11060-018-2840-6

Introduction
Although role of individual microRNAs (miRNAs) in the pathogenesis of gliomas has been well studied, their role as a clustered remains unexplored in gliomas.

Methods
In this study, we performed the expression analysis of miR-379/... Read More about Identification of miR-379/miR-656 (C14MC) cluster downregulation and associated epigenetic and transcription regulatory mechanism in oligodendrogliomas.

Novel internal regulators and candidate miRNAs within miR-379/miR-656 miRNA cluster can alter cellular phenotype of human glioblastoma (2018)
Journal Article
Nayak, S., Aich, M., Kumar, A., Sengupta, S., Bajad, P., Dhapola, P., …Sarkar, C. (2018). Novel internal regulators and candidate miRNAs within miR-379/miR-656 miRNA cluster can alter cellular phenotype of human glioblastoma. Scientific reports, 8(2018), #7673. https://doi.org/10.1038/s41598-018-26000-8

Clustered miRNAs can affect functioning of downstream pathways due to possible coordinated function. We
observed 78-88% of the miR-379/miR-656 cluster (C14MC) miRNAs were downregulated in three sub-types
of diffuse gliomas, which was also corrobora... Read More about Novel internal regulators and candidate miRNAs within miR-379/miR-656 miRNA cluster can alter cellular phenotype of human glioblastoma.