Dr Berna Sayan's Outputs (2)

Cleavage of the transactivation-inhibitory domain of p63 by caspases enhances apoptosis (2007)
Journal Article

p63 is a p53-related transcription factor. Utilization of two different promoters and alternative splicing at the C terminus lead to generation of six isoforms. The α isoforms of TAp63 and ΔNp63 contain a transactivation-inhibitory (TI) domain at the... Read More about Cleavage of the transactivation-inhibitory domain of p63 by caspases enhances apoptosis.

Generation of ΔTAp73 proteins by translation from a putative internal ribosome entry site (2007)
Journal Article

p73 belongs to a family of transcription factors, including p53 and p63, that mediate response to DNA damage and cellular stress by inducing DNA repair, cell cycle arrest, and apoptosis. TP73 gene contains two promotors and several splice variants re... Read More about Generation of ΔTAp73 proteins by translation from a putative internal ribosome entry site.