p73 and caspase-cleaved p73 fragments localize to mitochondria and augment TRAIL-induced apoptosis
(2008)
Journal Article
The p73 protein, a member of the p53 family, has both developmental and tumorigenic functions. Here we show that p73 is cleaved by caspase-3 and -8 both in vitro and in vivo during apoptosis elicited by DNA-damaging drugs and tumor necrosis factor-re... Read More about p73 and caspase-cleaved p73 fragments localize to mitochondria and augment TRAIL-induced apoptosis.